ECCO Topical Review on Pouch Disorders

Affiliations

¹ Icahn School of Medicine at Mount Sinai, Medicine/Gastroenterology, New York, NY, United States.
² Department of Abdominal Surgery, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
³ Department of Surgery, Cantonal Hospital of Fribourg and Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
⁴ Alfred Health, Gastroenterology, Melbourne, Australia.
⁵ CEMIC University Hospital, Colorectal Surgery, Buenos Aires, Argentina.
⁶ Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Canada.
⁷ Radboud University Medical Center, Gastroenterology, Nijmegen, the Netherlands.
⁸ Unidade Local de Saúde Gaia e Espinho, Department of Gastroenterology, Vila Nova de Gaia, Portugal.
⁹ IRCCS Hospital San Raffaele and University Vita-Salute San Raffaele, Gastroenterology and Endoscopy, Milan, Italy.
¹⁰ St. Mark's Hospital, IBD Unit, London, United Kingdom.
¹¹ Cleveland Clinic, Department of Colon & Rectal Surgery, Cleveland, OH, United States.
¹² University Hospital of Ghent, Department of Gastroenterology and Hepatology, Ghent, Belgium.
¹³ Rabin Medical Center, Gastroenterology, Petach Tikva, Israel.
¹⁴ Department of Gastroenterology and Hepatology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
¹⁵ Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.

PMID: 40574702
DOI: 10.1093/ecco-jcc/jjaf103

Review

ECCO Topical Review on Pouch Disorders

Maia Kayal et al. J Crohns Colitis. 2025.

. 2025 Jul 3;19(7):jjaf103.

doi: 10.1093/ecco-jcc/jjaf103.

Authors

Affiliations

¹ Icahn School of Medicine at Mount Sinai, Medicine/Gastroenterology, New York, NY, United States.
² Department of Abdominal Surgery, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
³ Department of Surgery, Cantonal Hospital of Fribourg and Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
⁴ Alfred Health, Gastroenterology, Melbourne, Australia.
⁵ CEMIC University Hospital, Colorectal Surgery, Buenos Aires, Argentina.
⁶ Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Canada.
⁷ Radboud University Medical Center, Gastroenterology, Nijmegen, the Netherlands.
⁸ Unidade Local de Saúde Gaia e Espinho, Department of Gastroenterology, Vila Nova de Gaia, Portugal.
⁹ IRCCS Hospital San Raffaele and University Vita-Salute San Raffaele, Gastroenterology and Endoscopy, Milan, Italy.
¹⁰ St. Mark's Hospital, IBD Unit, London, United Kingdom.
¹¹ Cleveland Clinic, Department of Colon & Rectal Surgery, Cleveland, OH, United States.
¹² University Hospital of Ghent, Department of Gastroenterology and Hepatology, Ghent, Belgium.
¹³ Rabin Medical Center, Gastroenterology, Petach Tikva, Israel.
¹⁴ Department of Gastroenterology and Hepatology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
¹⁵ Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.

PMID: 40574702
DOI: 10.1093/ecco-jcc/jjaf103

Abstract

Background: Pouch disorders are common and may present with symptoms of increased stool frequency, urgency, incontinence, pelvic cramping, obstructed defecation, and perianal drainage, which can result in poor sleep, fatigue, and disability. This topical review aims to offer expert consensus practice recommendations for the diagnosis and management of the most common inflammatory, functional, structural, and neoplastic J-pouch disorders.

Methods: A multidisciplinary panel of gastroenterologists and colorectal surgeons performed a systematic review of the relevant literature on pouch disorders and developed current practice positions.

Results: Seventeen current practice positions were developed on the diagnosis and management of inflammatory, functional, structural, and neoplastic pouch disorders.

Conclusions: A multidisciplinary approach is essential for the diagnosis and management of pouch disorders.

Keywords: pouch; pouchitis; proctocolectomy; ulcerative colitis.

© The Author(s) 2025. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

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ECCO Topical Review on Pouch Disorders

Affiliations

ECCO Topical Review on Pouch Disorders

Authors

Affiliations

Abstract

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical