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Case Reports
. 2025 Apr 30;33(2):251-256.
doi: 10.5606/tgkdc.dergisi.2025.25800. eCollection 2025 Apr.

Is it safe to perform coronary artery bypass grafting surgery in patients with hemophilia? A case series of four patients

Fatoş Dilan Köseoğlu  1 , Zühal Demirci  2 , Ümit Kahraman  3 , Güray Saydam  2 , Fahri Şahin  2
Affiliations
Case Reports

Is it safe to perform coronary artery bypass grafting surgery in patients with hemophilia? A case series of four patients

Fatoş Dilan Köseoğlu et al. Turk Gogus Kalp Damar Cerrahisi Derg. .

Abstract

Hemophilia is a genetic disorder that mainly affects males and leads to a higher risk of bleeding. There is a lack of clarity regarding the safety of coronary artery bypass grafting (CABG) surgery in patients with hemophilia. In this case series, real-life data of four male hemophilia patients aged 45 to 66 years who underwent CABG was presented. One patient needed to undergo reexploration due to nonsurgical bleeding. However, all patients were discharged in good condition. The current experience revealed that CABG in hemophilia patients is safe to perform with a multidisciplinary approach involving hematologists, anesthesiologists, and cardiovascular surgeons.

Keywords: Cardiovascular disease; coronary artery bypass grafting; hemophilia; surgery.

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Conflict of interest statement

Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

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References

    1. Bolliger D, Vandyck K, Tanaka KA. Management of patients with hemophilia undergoing cardiac surgery. J Cardiothorac Vasc Anesth. 2022;36:539–541. doi: 10.1053/j.jvca.2021.11.022. - DOI - PubMed
    1. Morfini M, Rapisarda CAP. Safety of recombinant coagulation factors in treating hemophilia. Expert Opin Drug Saf. 2019;18:75–85. doi: 10.1080/14740338.2019.1574743. - DOI - PubMed
    1. White GC 2nd, Rosendaal F, Aledort LM, Lusher JM, Rothschild C, Ingerslev J, Factor VIII and Factor IX Subcommittee Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost. 2001;85:560–560. - PubMed
    1. Bhave P, McGiffin D, Shaw J, Walsh M, McCarthy P, Tran H, et al. Guide to performing cardiac surgery in patients with hereditary bleeding disorders. J Card Surg. 2015;30:61–69. doi: 10.1111/jocs.12464. - DOI - PubMed
    1. Berntorp E, Fischer K, Hart DP, Mancuso ME, Stephensen D, Shapiro AD, et al. Haemophilia. Nat Rev Dis Primers. 2021;7:45–45. doi: 10.1038/s41572-021-00278-x. - DOI - PubMed

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