Experimental and clinical therapy of diabetes by transplantation
- PMID: 405769
Experimental and clinical therapy of diabetes by transplantation
Abstract
Prevention, delay, or reversal of the microvascular complications of diabetes is the ultimate goal of pancreatic islet cell transplantation. Advances in surgical techniques and in islet isolation procedures have made the achievement of this goal a practical possibility. Microvascular lesions have indeed been prevented and even reversed in successful islet cell transplantation experiments in rats. Successful application of pancreatic islet cell transplantation in the human now awaits the development of effective suppression of rejection.
Similar articles
-
Pancreatic transplantation as a means of insulin delivery.Diabetes Care. 1982 May-Jun;5 Suppl 1:93-7. Diabetes Care. 1982. PMID: 6821308 Review.
-
Replacement of pancreatic beta cells as treatment for diabetes mellitus: a review.Surg Annu. 1978;10:1-21. Surg Annu. 1978. PMID: 416507 Review.
-
Transplantation of islet cells--isografts and allografts.Monogr Pathol. 1980;21:156-65. Monogr Pathol. 1980. PMID: 6971401
-
[Islet cell transplantation and diabetes (author's transl)].Nouv Presse Med. 1979 Mar 24;8(14):1171-6. Nouv Presse Med. 1979. PMID: 111221 French.
-
Transplantation of islet tissue in the rat.Acta Endocrinol Suppl (Copenh). 1976;205:257-81. Acta Endocrinol Suppl (Copenh). 1976. PMID: 826063
Cited by
-
Pancreas and islet transplantation. I. Experimental studies.Diabetologia. 1981 Mar;20(3):161-85. doi: 10.1007/BF00252624. Diabetologia. 1981. PMID: 6785136 Review. No abstract available.
-
Prospects for pancreatic islet transplantation.World J Surg. 1986 Jun;10(3):410-21. doi: 10.1007/BF01655301. World J Surg. 1986. PMID: 3088849 Review. No abstract available.
-
Effect of amino-acids on secretion of insulin by isolated islets of the monkey.Diabetologia. 1982 Dec;23(6):541-3. doi: 10.1007/BF00254308. Diabetologia. 1982. PMID: 6818083