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Randomized Controlled Trial
. 2025 Jul;37(3):173-186.
doi: 10.1521/aeap.2025.37.3.173.

Feasibility of the Adapted MyPEEPS Mobile App for HIV Prevention in Young Transgender Men

Rebecca Schnall  1 , Asa Radix  2 , Lisa M Kuhns  3 , Patrick Janulis  4 , Christian Paredes  1 , Robert Garofalo  3
Affiliations
Randomized Controlled Trial

Feasibility of the Adapted MyPEEPS Mobile App for HIV Prevention in Young Transgender Men

Rebecca Schnall et al. AIDS Educ Prev. 2025 Jul.

Abstract

Transgender youth in the U.S. have unique health needs but often face barriers to accessing and receiving health care services, which contribute to disparate health outcomes including high risk for HIV acquisition. This article reports on a pilot randomized clinical trial of MyPEEPS Mobile for young transgender men (YTM) versus delayed intervention on condomless receptive anal and vaginal acts at 3 and 6 months after baseline. Participants rated the app as highly usable. Retention rates at 3 and 6 months were 89%. There were lower rates of condomless anal or vaginal sex acts during the intervention periods, but this reduction was not significantly different versus nonintervention periods. There was a higher likelihood of nPEP and PrEP use and HIV/STI testing during intervention periods, but this increase was not significantly different than nonintervention periods. Findings from the study support the feasibility of MyPEEPS Mobile for HIV prevention in YTM.

Keywords: HIV prevention; adolescents; mHealth; transgender men; young adults.

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Figures

FIGURE 1.
FIGURE 1.
Screenshots of the MyPEEPS Mobile YTM app.
FIGURE 2.
FIGURE 2.
CONORT study diagram.
See this image and copyright information in PMC

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