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. 2025 Jul-Aug;39(4):2357-2362.
doi: 10.21873/invivo.14033.

Penile Oxygen Saturation in Japanese Men Before and After Robot-assisted Radical Prostatectomy

Ryo Sato  1   2 , Toshiki Ito  3 , Kyohei Watanabe  4 , Yuto Matsushita  4 , Hiromitsu Watanabe  4 , Keita Tamura  4 , Daisuke Motoyama  4   5 , Atsushi Otsuka  4 , Hideaki Miyake  6
Affiliations

Penile Oxygen Saturation in Japanese Men Before and After Robot-assisted Radical Prostatectomy

Ryo Sato et al. In Vivo. 2025 Jul-Aug.

Abstract

Background/aim: The aim of this study was to investigate changes in penile oxygen saturation in Japanese patients before and after robot-assisted radical prostatectomy (RARP).

Patients and methods: The present study included 33 Japanese patients who underwent RARP between June 2018 and February 2024. Tissue oxygen saturation (StO2) was measured in the glans, bilateral corpora, and both thighs before and after surgery using Toccare™, a tissue oximeter.

Results: Nerve-sparing procedures were achieved as follows: right side, 16 patients (48.5%); left side, 11 (33.3%); bilateral, 4 (12.1%); none, 2 (6.1%). In all patients, no significant difference was observed in StO2 in the bilateral thighs before and after surgery, whereas a significant decrease was noted in the glans and bilateral corpora after surgery. StO2 in the glans and bilateral corpora significantly decreased in 20 patients in the right-side nerve-sparing group and 15 in the left-side nerve-sparing group, and nerve-sparing procedures did not correlate with changes in StO2.

Conclusion: StO2 in the glans and bilateral corpora decrease after RARP irrespective of whether a nerve-sparing procedure is performed.

Keywords: Penile oxygen saturation; erectile dysfunction; robot-assisted radical prostatectomy; tissue oximeter.

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Conflict of interest statement

The Authors declare that they have no conflicts of interest in relation to this study.

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