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Review
. 2025 Jun 27:emermed-2024-214669.
doi: 10.1136/emermed-2024-214669. Online ahead of print.

Management of haemophilia and heritable bleeding disorders in the ED

Elizabeth Helen Horn  1   2 , Kate Forsyth  3 , Richard Gooding  4 , Richard Gorman  5 , Deepan Gosrani  6 , David Hopper  7 , Jason Mainwaring  8 , Charles Llewellyn Percy  9 , Will Thomas  10 , Simon Smith  11 ; UK Haemophilia Doctors Organisation Task Force on Emergency Care
Collaborators, Affiliations
Review

Management of haemophilia and heritable bleeding disorders in the ED

Elizabeth Helen Horn et al. Emerg Med J. .

Abstract

This practice review addresses the management of haemophilia and heritable bleeding disorders in the ED. These disorders are uncommonly encountered by the emergency physician, but prompt and appropriate management is critical to ensure good outcomes. This practice review describes the principles of emergency care for people with bleeding disorders, with an emphasis on a pragmatic clinical approach, and provides examples of challenging emergencies.

Keywords: Emergency Medicine; Hemophilia A; acute care; hematology; triage.

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Conflict of interest statement

Competing interests: The following authors have received support for attendance at conferences related to haemophilia: KF from Sobi, R Gooding from Roche and from Sobi, DG from CSL Behring, Roche and Sobi, EHH from Roche and CSL Behring, WT from CSL Behring and Novo Nordisk. The following authors have received honoraria for writing a manuscript or providing a lecture: R Gooding from Sobi, R Gorman from Pfizer, DG from Sobi, DH from Sobi, CLP from Sobi, WT from Bayer, Pfizer, AstraZeneca, Takeda, Novo Nordisk, CSL Behring, Alexion, Portola, Sanofi and Sobi. The following authors have provided external consultancy: R Gooding for Sobi, CLP for Sobi, WT for Pfizer, AstraZeneca, Sanofi, Ablynx, Takeda, Novo Nordisk, Grifols, LFB Biopharmaceuticals. JM and SS provided statements indicating no competing interests. EHH is the chair of the UK Haemophilia Doctors Organisation Emergency Care Task Force: unpaid. DH is the chair of the Haemophilia Chartered Physiotherapy Association: unpaid.

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