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Review
. 2025 Nov;50(11):953-955.
doi: 10.1016/j.tibs.2025.06.010. Epub 2025 Jun 27.

Cell-specific mitoproteomics reveals mitochondrial plasticity and applications

Affiliations
Review

Cell-specific mitoproteomics reveals mitochondrial plasticity and applications

Domingos F M Neto et al. Trends Biochem Sci. 2025 Nov.

Abstract

Understanding the tissue-specific mitochondrial proteome is essential for advancing understanding of plant biology. In a recent study, Boussardon et al. applied Isolation of Mitochondria Tagged in Specific Cell Types (IMTACT) to investigate mitoproteome dynamics during pollen development. Here, we explore the broader potential of high-purity mitochondrial isolation in elucidating specific roles across tissues and developmental stages.

Keywords: mitochondrial proteomics; plant stress; single cell mitochondria.

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Conflict of interest statement

Declaration of interests None declared by authors.

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