Engineering insect-microbe symbiosis: synthetic microbial communities for sustainable insect management

Fangyuan Ye¹, Sibao Wang², Hao Zheng³

Affiliations

¹ College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, 100083, China.
² New Cornerstone Science Laboratory, CAS Key Laboratory of Insect Developmental and Evolutionary Biology, State Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China; CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing, China. Electronic address: sbwang@cemps.ac.cn.
³ College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, 100083, China. Electronic address: hao.zheng@cau.edu.cn.

PMID: 40582907
DOI: 10.1016/j.pt.2025.06.003

Review

Engineering insect-microbe symbiosis: synthetic microbial communities for sustainable insect management

Fangyuan Ye et al. Trends Parasitol. 2025 Aug.

. 2025 Aug;41(8):613-616.

doi: 10.1016/j.pt.2025.06.003. Epub 2025 Jun 28.

Authors

Fangyuan Ye¹, Sibao Wang², Hao Zheng³

Affiliations

¹ College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, 100083, China.
² New Cornerstone Science Laboratory, CAS Key Laboratory of Insect Developmental and Evolutionary Biology, State Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China; CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing, China. Electronic address: sbwang@cemps.ac.cn.
³ College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, 100083, China. Electronic address: hao.zheng@cau.edu.cn.

PMID: 40582907
DOI: 10.1016/j.pt.2025.06.003

Abstract

Insect-microbe symbiosis enables innovative modulation of insect biology via gut microbiota engineering. Synthetic microbial communities enhance pathogen resistance, nutrient provisioning, and host fitness. Engineering components of insect microbiomes enables precise manipulation of insect-microbe dynamics, advancing ecofriendly pest control and beneficial insect conservation while addressing biosafety and stability challenges.

Keywords: insects; synthetic microbial communities.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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Engineering insect-microbe symbiosis: synthetic microbial communities for sustainable insect management

Affiliations

Engineering insect-microbe symbiosis: synthetic microbial communities for sustainable insect management

Authors

Affiliations

Abstract

Conflict of interest statement

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MeSH terms

LinkOut - more resources

Full Text Sources