Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Aug;51(8):1563-1564.
doi: 10.1007/s00134-025-08011-y. Epub 2025 Jun 30.

OPTPRESS or OPTPRESSIN? Authors' reply

Affiliations

OPTPRESS or OPTPRESSIN? Authors' reply

Akira Endo et al. Intensive Care Med. 2025 Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declarations. Conflicts of interest: The authors declare no conflict of interest. Ethics statement: Not applicable.

References

    1. Shi R, Wu J, Teboul JL (2025) OPTPRESS or OPTPRESSIN?. Intensive Care Med. https://doi.org/10.1007/s00134-025-08000-1 - DOI
    1. Endo A, Yamakawa K, Tagami T et al (2025) Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial. Intensive Care Med 51:883–892. https://doi.org/10.1007/s00134-025-07910-4 - DOI
    1. Gordon AC, Mason AJ, Thirunavukkarasu N et al (2016) Effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock: The VANISH randomized clinical trial. JAMA 316:509–518. https://doi.org/10.1001/jama.2016.10485 - DOI
    1. Russell JA (2019) Vasopressor therapy in critically ill patients with shock. Intensive Care Med 45:1503–1517. https://doi.org/10.1007/s00134-019-05801-z - DOI
    1. Kalimouttou A, Kennedy JN, Feng J et al (2025) Optimal vasopressin initiation in septic shock: the OVISS reinforcement learning study. JAMA 333:1688–1698. https://doi.org/10.1001/jama.2025.3046 - DOI

LinkOut - more resources