Recent Progress in Multi-Analytes Recognition Reinforced by Graphene Derivatives for Cardio Health Assessments

Abstract

The escalating prevalence of cardiovascular diseases globally call for a low-cost monitoring technology for an immediate intervene and diagnoses. Advance multiplexed biosensors reinforced by graphene derivatives marks a significant progression in the field of cardiovascular health assessments. The graphene derived biosensors are designed specifically for fast detection of cardiac biomarkers with high precision to evaluate cardiovascular health. The graphene biocompatibility and fast signal transduction electronic properties provide an ideal foundation for the multiplexed technology. Despite the substantial potential of this multiplexed technologies, there remains a pressing need for further research and development to fully harness their capabilities in clinical environments. This study underscores the critical role of these biosensors in point of care applications and reviews the current landscape of research, highlighting significant progress made in graphene-based transduction and the recent trends in graphene production which give impact on biosensors performance. Key components are discussed include the assessment of vital cardiac biomarkers and the evolution of multiplex biosensing strategies that utilizes graphene nanomaterials. In summary, this review provides a comprehensive overview of the latest advancements in multi-analyte detection for cardiac healthcare. It outlines the key challenges encountered while proposing potential strategies to improve the effectiveness of multiplex biosensing platforms, thereby supporting the advancement of cardiac diagnostics. The potential of multiplexed biosensing technology leads to enhance diagnostic capabilities while reducing healthcare costs represents a significant advancement in cardiovascular healthcare, particularly for point-of-care applications.

Keywords: Cardiac biomarkers; graphene oxide; multi-analyte detection; multiplexed biosensors; reduced graphene oxide.