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Case Reports
. 2025 Jun 22:2025:1426202.
doi: 10.1155/crog/1426202. eCollection 2025.

Recurrent Pelvic Inflammatory Disease After Serial Intrauterine Inseminations

Lubos Karasek  1   2 , Pavla Svobodova  1 , Imrich Kiss  1 , Jan Smetana  2
Affiliations
Case Reports

Recurrent Pelvic Inflammatory Disease After Serial Intrauterine Inseminations

Lubos Karasek et al. Case Rep Obstet Gynecol. .

Abstract

Introduction: Intrauterine insemination is a basic method of assisted reproduction. It enables direct deposition of sperm inside the uterine cavity. The complications are rare. Multiple pregnancy or ovarian hyperstimulation can occur when concomitant ovulation induction is performed. The risk of pelvic inflammatory disease due to the artificial cervical barrier breach is very low, but the possible consequences are serious. Case presentation: We present a case of recurrent pelvic inflammatory disease following consecutive intrauterine inseminations. Pelvic inflammatory disease pathophysiology and treatment approaches are discussed. Conclusion: Inflammatory complications of the IUI are rare, but the possible impact on fertility can be devastating. Prevention of the PID together with prompt diagnosis and individualized therapy should be assured to preserve fertility.

Keywords: acute pelvic pain; intrauterine insemination; pelvic inflammatory disease; sexually transmitted infection; sterility.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Timeline of the case.
Figure 2
Figure 2
Transvaginal sonography finding in the right adnexal region after the first PID episode.
Figure 3
Figure 3
Transvaginal sonography findings in the left adnexal region after the second PID episode.
See this image and copyright information in PMC

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