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. 2025 Jul 1;135(13):e195673.
doi: 10.1172/JCI195673.

Vaccines in cancer treatment and prevention: the time is now

William Becker  1 , W Kimryn Rathmell  2
Affiliations

Vaccines in cancer treatment and prevention: the time is now

William Becker et al. J Clin Invest. .
No abstract available

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Conflict of interest statement

Conflict of interest: The authors have declared that no conflict of interest exists.

Figures

Figure 1
Figure 1. The process and effects of neoantigen vaccines to bring specificity to tumor immune response.
(A) A flow chart depicting the stages from tumor biopsy to tumor cell sequencing, to neoantigen identification, to mRNA-based neoantigen vaccine administration. (B) Antibody immunotherapy activates a range of T cells in the body, with a low proportion of T cells specific to the cancer. (C) A neoantigen vaccine can stimulate the patient’s T cells to be optimally targeted against antigens specific to the cancer, and the addition of antibody immunotherapies to the neoantigen vaccine stimulates the response of T cells to attack the cancer.
See this image and copyright information in PMC

References

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