Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jun 10:107655.
doi: 10.1016/j.amepre.2025.107655. Online ahead of print.

Adolescent Cannabis Vaping Trends (2021-2023): Delta-9-Tetrahydrocannabinol, Cannabidiol, and Synthetic Cannabinoids

Affiliations
Free article

Adolescent Cannabis Vaping Trends (2021-2023): Delta-9-Tetrahydrocannabinol, Cannabidiol, and Synthetic Cannabinoids

Jack Chung et al. Am J Prev Med. .
Free article

Abstract

Introduction: This study tracks national prevalence trends in the vaping of different cannabinoids among U.S. youths. Current (past 30-day) adolescent vaping prevalence of delta-9-tetrahydrocannabinol, cannabidiol, and synthetic cannabinoids from 2021 to 2023 was estimated.

Methods: Data came from 3 National Youth Tobacco Survey waves for the years 2021 (n=20,128), 2022 (n=27,965), and 2023 (n=21,806), comprising a total of 69,899 U.S. middle- and high-school students (aged 11-18 years). The population estimates and the weighted prevalence of current adolescent vaping of delta-9-tetrahydrocannabinol, cannabidiol, and synthetic cannabinoids were estimated by survey year and separately by age and biological sex. Analyses were conducted in 2024.

Results: There was a significant increase in adolescent vaping of delta-9-tetrahydrocannabinol, cannabidiol, and synthetic cannabinoids from 2021 to 2023. Delta-9-tetrahydrocannabinol vaping peaked in 2022, whereas the use of synthetic cannabinoids continued to increase. It is estimated that 7.4% (or 2.55 million) of U.S. adolescents were currently vaping delta-9-tetrahydrocannabinol, whereas 2.9% (or 999,000) were vaping cannabidiol, and 1.8% (or 620,000) were vaping synthetic cannabinoids in 2023. Notably, the prevalence of delta-9-tetrahydrocannabinol, cannabidiol, and synthetic cannabinoids vaping was higher among females than among males in 2023, where prevalence of both delta-9-tetrahydrocannabinol and synthetic cannabinoids vaping among those aged 11-13 years doubled between 2021 and 2023. In addition, uncertain respondents answering don't know whether they had vaped synthetic cannabinoids, tripled across the years.

Conclusions: This study reveals that vaping of delta-9-tetrahydrocannabinol, cannabidiol, and synthetic cannabinoids has increased among U.S. adolescents from 2021 to 2023. Further research is essential to understand the nature of adolescent cannabis vaping and its implications on youth health.

PubMed Disclaimer

LinkOut - more resources