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Review
. 2025 Jul 1:e70066.
doi: 10.1111/tid.70066. Online ahead of print.

Measles and Solid Organ Transplantation: Diagnosis, Treatment, and Prevention

Stephanie M Pouch  1 , Akshatha Ravindra  2 , Sara W Dong  3 , Wanessa Trindade Clemente  4 , Ricardo M La Hoz  5 , Aaron Mishkin  6 , Jonathan Hand  7 , Maristela Pinheiro Freire  8 , Jacques Simkins  9 , Cameron Wolfe  10 , John W Baddley  11
Affiliations
Review

Measles and Solid Organ Transplantation: Diagnosis, Treatment, and Prevention

Stephanie M Pouch et al. Transpl Infect Dis. .

Abstract

The recent international resurgence of measles has led to significant public health concerns and poses significant risks to immunocompromised patients, including those who have undergone solid organ transplantation (SOT). SOT recipients may present atypically and are at an increased risk of severe complications of measles infection, underscoring the importance of preventative measures. This review summarizes contemporary data regarding measles transmission, the clinical presentation, diagnosis, and treatment of SOT recipients, as well as strategies for measles prevention, infection control considerations, postexposure prophylaxis, and opportunities for the mitigation of donor-derived measles and measles vaccine viruses.

Keywords: donor‐derived infection; measles; postexposure prophylaxis; solid organ transplantation; vaccination.

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