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Review
. 2025 Mar 20;56(2):556-562.
doi: 10.12182/20250360102.

[Epidural Analgesia in Minimally Invasive Esophagectomy: Evidence and Practice]

[Article in Chinese]
Affiliations
Review

[Epidural Analgesia in Minimally Invasive Esophagectomy: Evidence and Practice]

[Article in Chinese]
Bihua Xie et al. Sichuan Da Xue Xue Bao Yi Xue Ban. .

Abstract

Esophagectomy is an effective treatment for esophageal cancer, and there has been growing attention on the importance of postoperative pain management in patients undergoing the surgery. Epidural analgesia is the preferred analgesic approach for open esophagectomy. With the development of surgical technology, minimally invasive esophagectomy (MIE) has become the mainstream surgical approach. However, no conclusion has been reached concerning whether epidural analgesia is still the preferred analgesic approach for MIE. Herein, we analyzed the relevant literature published in recent years and found that epidural analgesia continued to be an important analgesic approach for MIE, offering the best analgesic effect. Epidural analgesia can reduce postoperative pulmonary complications, improve the quality of life, and reduce the stress response. Adverse effects can be minimized through accurate selection of epidural puncture segments, individualized medication, and multimodal analgesia strategies. In the future, precision-based multimodal analgesia can be achieved using emerging technologies such as big data analytics and artificial intelligence.

食管切除术作为治疗食管癌的有效手段,其术后疼痛管理的重要性日益受到关注,硬膜外镇痛是开放食管切除术首选的镇痛方式。随着外科技术的发展,微创食管切除术(minimally invasive esophagectomy, MIE)已成为主流手术方式,硬膜外镇痛是否仍是MIE的首选镇痛方式,目前尚无定论。本综述通过分析近年来的相关文献,发现硬膜外镇痛仍然是MIE的重要镇痛方式,镇痛效果最佳,可以减少肺部并发症,改善生活质量,减少应激反应。通过准确选择穿刺节段、个体化用药和多模式镇痛可以减少不良反应。未来可以使用大数据和人工智能达到精准多模式镇痛。

Keywords: Analgesia, epidural; Complications; Esophagectomy; Minimally invasive surgical procedures; Review.

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Conflict of interest statement

利益冲突 所有作者均声明不存在利益冲突

Figures

图 1
图 1
Application of epidural analgesia in minimally invasive esophagectomy in Sankey diagram visualization 硬膜外镇痛在MIE术中应用相关文献桑基图 RCT: randomized controlled trial; MIE: minimally invasive esophagectomy.
图 2
图 2
A comparative study of different analgesic methods in MIE 不同镇痛方式在MIE术后镇痛的对照研究 The size of the nodes corresponds to the sample size of the study. The lines linking the nodes represent the comparison of the two analgesic methods. The thicker the line, the more published reports comparing the two analgesic methods.

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