Editorial: Mechanisms of early intracellular signaling in T lymphocytes
- PMID: 40599772
- PMCID: PMC12208825
- DOI: 10.3389/fimmu.2025.1638330
Editorial: Mechanisms of early intracellular signaling in T lymphocytes
Keywords: CAR-T signaling; T cell activation; T lymphocytes; TCR; adaptor proteins; thymic development.
Conflict of interest statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Comment on
- Editorial on the Research Topic: Mechanisms of early intracellular signaling in T lymphocytes
Similar articles
-
MyD88 determines T cell fate through BCAP-PI3K signaling.J Immunol. 2025 Mar 1;214(3):433-445. doi: 10.1093/jimmun/vkae037. J Immunol. 2025. PMID: 40073160
-
Impaired thymic selection in mice expressing altered levels of the SLP-76 adaptor protein.J Leukoc Biol. 2008 Feb;83(2):419-29. doi: 10.1189/jlb.0507297. Epub 2007 Oct 26. J Leukoc Biol. 2008. PMID: 17965338
-
The Role of Adaptor Proteins in the Biology of Natural Killer T (NKT) Cells.Front Immunol. 2019 Jun 25;10:1449. doi: 10.3389/fimmu.2019.01449. eCollection 2019. Front Immunol. 2019. PMID: 31293596 Free PMC article. Review.
-
Cortical Thymic Epithelial Cells: Key Developers of the Code of T-Cell Selection and TCR Repertoire Diversity.Immunol Rev. 2025 Jul;332(1):e70049. doi: 10.1111/imr.70049. Immunol Rev. 2025. PMID: 40558027 Review.
-
Next-Generation CAR-T and TCR-T Cell Therapies for Solid Tumors: Innovations, Challenges, and Global Development Trends.Cancers (Basel). 2025 Jun 11;17(12):1945. doi: 10.3390/cancers17121945. Cancers (Basel). 2025. PMID: 40563595 Free PMC article. Review.
References
-
- Arbulo-Echevarria MM, Vico-Barranco I, Zhang F, Fernandez-Aguilar LM, Chotomska M, Narbona-Sanchez I, et al. Mutation of the glycine residue preceding the sixth tyrosine of the LAT adaptor severely alters T cell development and activation. Front Immunol. (2022) 13:1054920. doi: 10.3389/fimmu.2022.1054920 - DOI - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources