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. 2025 Jul 2;5(7):e0004616.
doi: 10.1371/journal.pgph.0004616. eCollection 2025.

Strengthening anal cancer prevention in Abuja, Nigeria: Identifying barriers and potential strategies to improve training

Connor R Volpi  1 , John Chama  2 , Megan E Mansfield  3 , Ruxton Adebiyi  2 , Andrew Mitchell  3 , Jumoke A Aigoro  2 , Yerima Jibrin Bawa  2 , Kazeem E Kolawole  2 , Uchenna Ononaku  2 , Paul Jibrin  4 , Oluwole Olaomi  4 , Francis Agbo  5 , Soren M Bentzen  6 , Stephen E Goldstone  7 , Patrick Dakum  2 , Joel M Palefsky  8 , Cheryl Knott  9 , Sylvia Adebajo  2 , Rebecca G Nowak  3   6
Affiliations

Strengthening anal cancer prevention in Abuja, Nigeria: Identifying barriers and potential strategies to improve training

Connor R Volpi et al. PLOS Glob Public Health. .

Abstract

Anal cancer poses a significant risk for sexual minority males (SMM) living with HIV, with a 100-fold higher incidence compared to the general population. Despite success in high-income settings, training on anal cancer prevention in Africa faces challenges due to limited resources and lack of trained practitioners. We evaluated adapting training using an implementation science framework in a Nigerian SMM-friendly clinic. The Consolidated Framework for Implementation Research (CFIR) Card Game assessed barriers to training on anal cancer prevention. Stakeholders ranked the importance of different CFIR constructs. Sessions were conducted separately for internal stakeholders, external stakeholders, and patients. Facilitators identified barriers using culturally adapted text and a hybrid format for consensus discussion. Potential strategies to overcome the barriers were identified with the CFIR-Expert Recommendations for Implementing Change (ERIC) Matching Tool. The CFIR card game was conducted in August 2023 with 20 participants (Internal: 4, External: 8, Patients: 8). Internal stakeholders identified adaptability, cost, and the absence of external change agents. External stakeholders highlighted adaptability, design quality, and financial burden, proposing advocacy and local discussions. Patients expressed concerns about adaptability and external policies affecting trust and acceptance, emphasizing strategic adaptations and local involvement. The CFIR-ERIC Matching Tool recommended identifying champions and altering incentives as strategies. Incorporating champion roles, local adaptations, policy enforcement, and financial support can enhance training on anal cancer prevention in Nigeria. The findings stress the importance of cultural sensitivity and engagement with local stakeholders to support training practitioners in anal cancer prevention.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Barriers Identification Process.
See this image and copyright information in PMC

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References

    1. Frisch M, Biggar RJ, Goedert JJ. Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Natl Cancer Inst. 2000;92(18):1500–10. doi: 10.1093/jnci/92.18.1500 - DOI - PubMed
    1. Colón-López V, Shiels MS, Machin M, Ortiz AP, Strickler H, Castle PE, et al. Anal Cancer Risk Among People With HIV Infection in the United States. J Clin Oncol. 2018;36(1):68–75. doi: 10.1200/JCO.2017.74.9291 - DOI - PMC - PubMed
    1. Bedimo R, Chen RY, Accortt NA, Raper JL, Linn C, Allison JJ, et al. Trends in AIDS-Defining and Non—AIDS-Defining Malignancies among HIV-Infected Patients: 1989–2002. Clin Infect Dis. 2004;39(9):1380–4. - PubMed
    1. Diamond C, Taylor TH, Aboumrad T, Bringman D, Anton-Culver H. Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy. Sexually Transmitted Dis. 2005;:314–20. - PubMed
    1. Clifford GM, Georges D, Shiels MS, Engels EA, Albuquerque A, Poynten IM, et al. A meta-analysis of anal cancer incidence by risk group: Toward a unified anal cancer risk scale. Int J Cancer. 2021;148(1):38–47. doi: 10.1002/ijc.33185 - DOI - PMC - PubMed

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