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. 2025 Jul 2;25(1):514.
doi: 10.1186/s12887-025-05861-9.

The association between short-term postoperative complications and bowel function after surgery for Hirschsprung disease

Zhengxing Jiang  1 , Jinping Hou  1 , Xiaohong Die  1 , Wei Liu  1 , Yujie Wang  1 , Hongyang Li  1 , Wei Feng  2 , Yi Wang  3
Affiliations

The association between short-term postoperative complications and bowel function after surgery for Hirschsprung disease

Zhengxing Jiang et al. BMC Pediatr. .

Abstract

Objective: This study aims to investigate the relationship between postoperative short-term complications and bowel function in patients with Hirschsprung disease (HSCR), and to explore the risk factors affecting bowel function.

Methods: The medical records of 367 eligible patients diagnosed with HSCR were reviewed. According to the bowel function score (BFS), patients were divided into a normal bowel function group (200 cases, BFS > 17) and an abnormal bowel function group (167 cases, BFS ≤ 17), and the possible risk factors for poor bowel function were evaluated through univariate and multivariate analysis. According to the Clavien Madadi (CM) classification of complications, CM grades I and II were considered mild complications and CM III and IV were considered severe complications.

Results: According to binary logistic regression analysis, long-segment disease (OR = 3.255; 95% CI, 1.192-9.655; p = 0.026), formula feeding (OR = 3.081; 95% CI, 1.626-5.933; p = 0.001), mild complications (OR = 9.560; 95% CI, 4.261-24.01; p < 0.001), and severe complications (OR = 17.127; 95% CI, 4.280-116.6; p < 0.001) were independent risk factors for postoperative poor bowel function. The surgery age between 1 and 3 years (OR = 0.357; 95% CI, 0.158-0.791; p = 0.012) was associated with a reduction in the incidence of poor bowel function.

Conclusions: Postoperative complications, long-segment disease, and formula feeding are independent risk factors for postoperative poor bowel function in patients with HSCR. Further multicenter studies require larger sample sizes to clarify and confirm our findings.

Keywords: Bowel function; Clavien-Madadi classification; Hirschprung’s disease; Short-term postoperative complications.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: The information obtained from institutions was ethically approved by the Children’s Hospital of Chongqing Medical University. All procedures in the study were carried out in accordance with national ethical guidelines for medical and health research involving human subjects, as well as the 1964 Helsinki Declaration and its subsequent amendments (Date: 2021/No: 391). Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Bowel function scores in different complication groups. Note: ***, P < 0.001
See this image and copyright information in PMC

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