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. 2025 Jun 5;11(6):826-827.
doi: 10.1021/acscentsci.5c00926. eCollection 2025 Jun 25.

Light-Powered Late-Stage Alkylation of N‑Heteroaromatics in Flow

Shun Wang  1 , Zhiwei Zuo  1
Affiliations

Light-Powered Late-Stage Alkylation of N‑Heteroaromatics in Flow

Shun Wang et al. ACS Cent Sci. .

Abstract

Continuous-flow photochemistry allows late-stage functionalization of N-heteroaromatics with gaseous alkane.

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Figures

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(a) Optimization of reaction conditions. (b) Representative examples of late-stage alkylation of N-heteroarenes and scaling-up applications.
See this image and copyright information in PMC

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