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Case Reports
. 2025 Apr 11:61:133-135.
doi: 10.1016/j.jdcr.2025.03.029. eCollection 2025 Jul.

Abaloparatide-induced pseudoxanthoma elasticum

Sarah A Amjad  1 , Thais Pincelli  2 , Shon E Meek  3 , Olayemi Sokumbi  2 , James Keeling  2 , Elisha M Singer  2
Affiliations
Case Reports

Abaloparatide-induced pseudoxanthoma elasticum

Sarah A Amjad et al. JAAD Case Rep. .
No abstract available

Keywords: ABCC6; abaloparatide; calcium; elastorrhexis; osteoporosis; parathyroid-related peptide; pseudoxanthoma elasticum.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
A, Photograph of the skin of the patient’s left neck. B, Photograph of the skin of the patient’s left axillae. C, Photograph of the patient’s right antecubital fossa. All three photographs demonstrate yellow papules coalescing into cobblestoned plaques.
Fig 2
Fig 2
A, Punch biopsy obtained from the left anterior axillary crease demonstrates short and fragmented elastic fibers in the reticular dermis. B, The abnormal basophilic elastic fibers are readily identified (A, hematoxylin-eosin, original magnification ×4; B, hematoxylin-eosin, original magnification ×25).
See this image and copyright information in PMC

References

    1. Li Q., Jiang Q., Pfendner E., Váradi A., Uitto J. Pseudoxanthoma elasticum: clinical phenotypes, molecular genetics and putative pathomechanisms. Exp Dermatol. 2009;18(1):1–11. - PMC - PubMed
    1. Pfau K., Lengyel I., Ossewaarde-van Norel J., et al. Pseudoxanthoma elasticum - genetics, pathophysiology, and clinical presentation. Prog Retin Eye Res. 2024;102 - PMC - PubMed
    1. Nollet L., Campens L., De Zaeytijd J., et al. Clinical and subclinical findings in heterozygous ABCC6 carriers: results from a Belgian cohort and clinical practice guidelines. J Med Genet. 2022;59:496–504. - PubMed
    1. Ishak R., Abbas O. Penicillamine revisited: historic overview and review of the clinical uses and cutaneous adverse effects. Am J Clin Dermatol. 2013;14:223–233. - PubMed
    1. Bartstra J.W., Risseeuw S., de Jong P.A., et al. Genotype-phenotype correlation in pseudoxanthoma elasticum. Atherosclerosis. 2021;324:18–26. - PubMed

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