Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 Aug;51(8):1518-1521.
doi: 10.1007/s00134-025-08010-z. Epub 2025 Jul 3.

Hemodynamic targets in the initial resuscitation of older patients with sepsis: time for a reappraisal?

Julien Demiselle  1   2 , Ricard Ferrer  3   4   5 , Bruno Besen  6   7   8
Affiliations
Editorial

Hemodynamic targets in the initial resuscitation of older patients with sepsis: time for a reappraisal?

Julien Demiselle et al. Intensive Care Med. 2025 Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declarations. Conflict of interest: Ricard Ferrer is a Deputy Editor for Intensive Care Medicine journal. Other authors declare to have no conflicts of interest in relation with this manuscript. Ethics approval: Not applicable.

References

    1. Flaatten H, de Lange DW, Artigas A et al (2017) The status of intensive care medicine research and a future agenda for very old patients in the ICU. Intensive Care Med 43:1319–1328. https://doi.org/10.1007/s00134-017-4718-z - DOI
    1. Lamontagne F, Day AG, Meade MO et al (2018) Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. Intensive Care Med 44:12–21. https://doi.org/10.1007/s00134-017-5016-5 - DOI
    1. Lamontagne F, Richards-Belle A, Thomas K et al (2020) Effect of reduced exposure to vasopressors on 90-day mortality in older critically ill patients with vasodilatory hypotension: a randomized clinical trial. JAMA 323:938–949. https://doi.org/10.1001/jama.2020.0930 - DOI
    1. Endo A, Yamakawa K, Tagami T et al (2025) Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial. Intensive Care Med 51:883–892. https://doi.org/10.1007/s00134-025-07910-4 - DOI
    1. For the Canadian Critical Care Trials Group., Lamontagne F, Meade MO, et al (2016) Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial. Intensive Care Medicine 42:542–550. https://doi.org/10.1007/s00134-016-4237-3

Publication types

LinkOut - more resources