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. 2025 Jul 1:4:e69654.
doi: 10.2196/69654.

Enhancing Magnetic Resonance Imaging (MRI) Report Comprehension in Spinal Trauma: Readability Analysis of AI-Generated Explanations for Thoracolumbar Fractures

Affiliations

Enhancing Magnetic Resonance Imaging (MRI) Report Comprehension in Spinal Trauma: Readability Analysis of AI-Generated Explanations for Thoracolumbar Fractures

David C Sing et al. JMIR AI. .

Abstract

Background: Magnetic resonance imaging (MRI) reports are challenging for patients to interpret and may subject patients to unnecessary anxiety. The advent of advanced artificial intelligence (AI) large language models (LLMs), such as GPT-4o, hold promise for translating complex medical information into layman terms.

Objective: This paper aims to evaluate the accuracy, helpfulness, and readability of GPT-4o in explaining MRI reports of patients with thoracolumbar fractures.

Methods: MRI reports of 20 patients presenting with thoracic or lumbar vertebral body fractures were obtained. GPT-4o was prompted to explain the MRI report in layman's terms. The generated explanations were then presented to 7 board-certified spine surgeons for evaluation on the reports' helpfulness and accuracy. The MRI report text and GPT-4o explanations were then analyzed to grade the readability of the texts using the Flesch Readability Ease Score (FRES) and Flesch-Kincaid Grade Level (FKGL) Scale.

Results: The layman explanations provided by GPT-4o were found to be helpful by all surgeons in 17 cases, with 6 of 7 surgeons finding the information helpful in the remaining 3 cases. ChatGPT-generated layman reports were rated as "accurate" by all 7 surgeons in 11/20 cases (55%). In an additional 5/20 cases (25%), 6 out of 7 surgeons agreed on their accuracy. In the remaining 4/20 cases (20%), accuracy ratings varied, with 4 or 5 surgeons considering them accurate. Review of surgeon feedback on inaccuracies revealed that the radiology reports were often insufficiently detailed. The mean FRES score of the MRI reports was significantly lower than the GPT-4o explanations (32.15, SD 15.89 vs 53.9, SD 7.86; P<.001). The mean FKGL score of the MRI reports trended higher compared to the GPT-4o explanations (11th-12th grade vs 10th-11th grade level; P=.11).

Conclusions: Overall helpfulness and readability ratings for AI-generated summaries of MRI reports were high, with few inaccuracies recorded. This study demonstrates the potential of GPT-4o to serve as a valuable tool for enhancing patient comprehension of MRI report findings.

Keywords: AI; ChatGPT; LLM; MRI; artificial intelligence; large language model; magnetic resonance imaging; orthopedic surgery; patient education; spine surgery; thoracolumbar fracture; trauma.

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Conflict of interest statement

Conflicts of Interest: None declared by authors DCS, KSS, MP, PHY, CV, AB, and SRS.

Author RKE holds stock or stock options in Aclarion, Alphatec Spine, Orthofix, Inc; Nuvasive, and Spine Innovations. RKE receives IP royalties from Aesculap/B.Braun, Globus Medical, Nuvasive, Seaspine, and SI Bone. RKE is a paid consultant for Aesculap/B.Braun, Amgen Co, Johnson & Johnson, Kuros, Medtronic, Neo Spine, Nuvasive, Silony, Spinal Elements, and Seaspine. RKE receives research support from Medtronic, Sofamor Danek, Nuvasive, and Seaspine. RKE is a paid presenter or speaker for Radius and serves as a board and committee member for the San Diego Orthopaedic Research Society, San Diego Spine Foundation, and Scoliosis Research Society.

Author GMM Jr holds stock or stock options in Alphatec Spine, Nuvasive, and Orthofix, Inc. GMM Jr receives IP royalties from Nuvasive, Seaspine, and Stryker. GMM Jr is a paid consultant for Globus, Carlsmed, Seaspine, and SI Bone. GMM Jr receives research support from Medtronic, Sofamor Danek, Globus, and Orthofix. GMM Jr is a board or committee member for the Scoliosis Research Society, Society of Minimally Invasive Spine Surgery, San Diego Orthopaedic Society, Global Spine Outreach, and San Diego Spine Foundation.

Figures

Figure 1.
Figure 1.. This diagram showcases how deidentified magnetic resonance imaging (MRI) reports were processed through ChatGPT-4o with a prompt that asked to explain the imaging findings in layman’s terms for patient education purposes. The MRI report completed by the radiologist can be seen on the left in green, while a GPT-4o–generated, simplified version of the MRI report can be seen on the right in blue. Readability scores (Flesch Readability Ease Score) and reading grade levels (Flesch-Kincaid Grade Level) were determined for each version of the MRI report. AI: artificial intelligence.

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