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Editorial
. 2025 Jul;30(26):2500454.
doi: 10.2807/1560-7917.ES.2025.30.26.2500454.

Doxycycline post-exposure prophylaxis (doxyPEP): balancing promise and prudence in the prevention of sexually transmitted infections

Affiliations
Editorial

Doxycycline post-exposure prophylaxis (doxyPEP): balancing promise and prudence in the prevention of sexually transmitted infections

Fiona Lyons et al. Euro Surveill. 2025 Jul.
No abstract available

Keywords: doxyPEP; doxycycline; prophylaxis; sexually transmitted infections.

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Conflict of interest statement

Conflict of interest: None declared.

References

    1. European Centre for Disease Prevention and Control (ECDC). STI cases continue to rise across Europe. Stockholm: ECDC; 10 Feb 2025. Available from: https://www.ecdc.europa.eu/en/news-events/sti-cases-continue-rise-across...
    1. World Health Organization (WHO). Global health sector strategies on, respectively, HIV, viral hepatitis and sexually transmitted infections for the period 2022-2030. Geneva: WHO; 2022. Available from: https://www.who.int/publications/i/item/9789240053779
    1. Molina JM, Charreau I, Chidiac C, Pialoux G, Cua E, Delaugerre C, et al. Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial. Lancet Infect Dis. 2018;18(3):308-17. 10.1016/S1473-3099(17)30725-9 - DOI - PubMed
    1. Luetkemeyer AF, Donnell D, Dombrowski JC, Cohen S, Grabow C, Brown CE, et al. Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections. N Engl J Med. 2023;388(14):1296-306. 10.1056/NEJMoa2211934 - DOI - PMC - PubMed
    1. Molina JM, Bercot B, Assoumou L, Rubenstein E, Algarte-Genin M, Pialoux G, et al. Doxycycline prophylaxis and meningococcal group B vaccine to prevent bacterial sexually transmitted infections in France (ANRS 174 DOXYVAC): a multicentre, open-label, randomised trial with a 2 × 2 factorial design. Lancet Infect Dis. 2024;24(10):1093-104. 10.1016/S1473-3099(24)00236-6 - DOI - PubMed

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