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Comment
. 2025 Jul 3;85(13):2457-2459.
doi: 10.1016/j.molcel.2025.06.010.

Cellular metabolite sensors: Arginine? It's in the bag!

Thomas D Jackson  1 , Jonathan M Palozzi  1 , Pere Puigserver  2
Affiliations
Comment

Cellular metabolite sensors: Arginine? It's in the bag!

Thomas D Jackson et al. Mol Cell. .

Abstract

In this issue of Molecular Cell, Chen et al.1 identify a novel arginine-sensing system, composed of the cytosolic proteins BAG2 and SAMD4B, which promotes cancer cell survival during arginine deficiency.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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