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Comparative Study
. 1977 Apr;16(1):1-8.
doi: 10.1128/iai.16.1.1-8.1977.

Stimulation of macrophages by cord factor and by heat-killed and living BCG

E Yarkoni, L Wang, A Bekierkunst
Comparative Study

Stimulation of macrophages by cord factor and by heat-killed and living BCG

E Yarkoni et al. Infect Immun. 1977 Apr.

Abstract

Trehalose-6,6'-dimycolate (cord factor; CF) injected into the peritoneal cavity of mice induced stimulation of the peritoneal macrophages, evidenced both by increased activity of the lysosomal enzyme, acid phosphatase, and by increased phagocytosis of Listeria monocytogenes. The increase in enzyme activity and phagocytosis was similar to that induced by killed or living BCG. When administered intravenously, CF or BCG did not induce stimulation of peritoneal macrophages. CF when added to tissue cultures of normal peritoneal cells did not induce increased acid phosphatase activity or increased phagocytosis of L. monocytogenes.

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References

    1. Int J Cancer. 1975 Sep 15;16(3):442-7 - PubMed
    1. Infect Immun. 1976 Nov;14(5):1125-9 - PubMed
    1. Cell Immunol. 1975 Mar;16(1):11-24 - PubMed
    1. Infect Immun. 1976 Mar;13(3):776-81 - PubMed
    1. J Natl Cancer Inst. 1976 Dec;57(6):1379-81 - PubMed

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