Telomere Dysfunction in Renal Tubular Epithelial Cells Leads to Kidney Fibrosis

Affiliations

¹ Telomeres and Telomerase Group - Fundación Humanismo y Ciencia, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
² Confocal Microscopy Unit, Biotechnology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
³ Advanced Optical Microscopy Unit, UCCTs, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
⁴ Bioinformatics Unit, Structural Biology and Biocomputing Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
⁵ Department of Basic Medical Sciences, Institute of Applied Molecular Medicine (IMMA-Nemesio Díez), School of Medicine, San Pablo-CEU University, CEU Universities, Madrid, Spain.
⁶ Animal Surgery and Medicine Department, Faculty of Veterinary Science, Complutense University of Madrid, Madrid, Spain.

Sarita Saraswati et al. J Am Soc Nephrol. 2025.

. 2025 Jul 8.

doi: 10.1681/ASN.0000000771. Online ahead of print.

¹ Telomeres and Telomerase Group - Fundación Humanismo y Ciencia, Molecular Oncology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
² Confocal Microscopy Unit, Biotechnology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
³ Advanced Optical Microscopy Unit, UCCTs, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
⁴ Bioinformatics Unit, Structural Biology and Biocomputing Program, Spanish National Cancer Centre (CNIO), Madrid, Spain.
⁵ Department of Basic Medical Sciences, Institute of Applied Molecular Medicine (IMMA-Nemesio Díez), School of Medicine, San Pablo-CEU University, CEU Universities, Madrid, Spain.
⁶ Animal Surgery and Medicine Department, Faculty of Veterinary Science, Complutense University of Madrid, Madrid, Spain.

No abstract available

Keywords: AKI; CKD; interstitial fibrosis; renal epithelial cell; renal fibrosis; renal tubular epithelial cells; signaling; transgenic mouse.

References

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