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. 1985:80 Suppl 2:155-8.

Evidence from aequorin for injury of metabolically inhibited myocytes independently of free Ca2+

P H Cobbold, P K Bourne, S R Cuthbertson
  • PMID: 4062828

Evidence from aequorin for injury of metabolically inhibited myocytes independently of free Ca2+

P H Cobbold et al. Basic Res Cardiol. 1985.

Abstract

The calcium-sensitive photoprotein aequorin has been used to measure cytoplasmic free Ca in single rat ventricle myocytes during metabolic inhibition. Rounding-up of the myocytes, and blebbing of the surface, occurred while free Ca remained at normal resting levels of 1 to 3 X 10(-7)M. Control over free Ca is less susceptible to metabolic blockade than is structural organization.

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