[Effect of antihistaminics on bradykinin action]
[Article in
Russian]
- PMID: 40631
Item in Clipboard
[Effect of antihistaminics on bradykinin action]
[Article in
Russian]
Biull Eksp Biol Med.
1979 Oct.
Abstract
On isolated ileum of the guinea pig the antihistamine drugs dimedrol, diprazin (pipolphen), tavegil and suprastin diminished spasmogenic effects of bradykinin and an enhancement of microvascular permeability induced by this polypeptid. The antihistamine drugs display a nonspecific antibradykinin activity. No relationship between the chemical structure and pronounced antibradykinin action of the antihistamines studied was revealed.
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