Retraction Note: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis

Zaili Luo^#¹, Mingyang Xia^#², Wei Shi^#³, Chuntao Zhao^#¹, Jiajia Wang^#⁴, Dazhuan Xin¹, Xinran Dong², Yu Xiong^{5

6}, Feng Zhang¹, Kalen Berry¹, Sean Ogurek¹, Xuezhao Liu¹, Rohit Rao¹, Rui Xing¹, Lai Man Natalie Wu¹, Siying Cui², Lingli Xu², Yifeng Lin², Wenkun Ma⁴, Shuaiwei Tian⁴, Qi Xie⁷, Li Zhang¹, Mei Xin¹, Xiaotao Wang⁸, Feng Yue⁸, Haizi Zheng¹, Yaping Liu¹, Charles B Stevenson¹, Peter de Blank¹, John P Perentesis¹, Richard J Gilbertson⁹, Hao Li¹⁰, Jie Ma¹¹, Wenhao Zhou¹², Michael D Taylor¹³, Q Richard Lu¹⁴

Affiliations

¹ Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
² Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
³ Department of Neurosurgery, Children's Hospital of Fudan University, Shanghai, China.
⁴ Department of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁵ Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
⁶ Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, China.
⁷ School of Life Sciences, Westlake University, Hangzhou, China.
⁸ Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.
⁹ Cancer Research UK Cambridge Centre, CRUK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK.
¹⁰ Department of Neurosurgery, Children's Hospital of Fudan University, Shanghai, China. lihao7272@163.com.
¹¹ Department of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. majie@xinhuamed.com.cn.
¹² Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China. zhouwenhao@fudan.edu.cn.
¹³ Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
¹⁴ Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Richard.Lu@cchmc.org.

^# Contributed equally.

PMID: 40634621
DOI: 10.1038/s41586-025-09015-w

Retraction Note: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis

Zaili Luo et al. Nature. 2025 Aug.

. 2025 Aug;644(8075):290.

doi: 10.1038/s41586-025-09015-w.

Authors

Affiliations

¹ Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
² Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China.
³ Department of Neurosurgery, Children's Hospital of Fudan University, Shanghai, China.
⁴ Department of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁵ Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
⁶ Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, China.
⁷ School of Life Sciences, Westlake University, Hangzhou, China.
⁸ Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.
⁹ Cancer Research UK Cambridge Centre, CRUK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK.
¹⁰ Department of Neurosurgery, Children's Hospital of Fudan University, Shanghai, China. lihao7272@163.com.
¹¹ Department of Pediatric Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. majie@xinhuamed.com.cn.
¹² Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Fudan University, Shanghai, China. zhouwenhao@fudan.edu.cn.
¹³ Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
¹⁴ Brain Tumor Center, Division of Experimental Hematology and Cancer Biology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Richard.Lu@cchmc.org.

^# Contributed equally.

PMID: 40634621
DOI: 10.1038/s41586-025-09015-w

No abstract available

PubMed Disclaimer

Retraction of

Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis.
Luo Z, Xia M, Shi W, Zhao C, Wang J, Xin D, Dong X, Xiong Y, Zhang F, Berry K, Ogurek S, Liu X, Rao R, Xing R, Wu LMN, Cui S, Xu L, Lin Y, Ma W, Tian S, Xie Q, Zhang L, Xin M, Wang X, Yue F, Zheng H, Liu Y, Stevenson CB, de Blank P, Perentesis JP, Gilbertson RJ, Li H, Ma J, Zhou W, Taylor MD, Lu QR. Luo Z, et al. Nature. 2022 Dec;612(7941):787-794. doi: 10.1038/s41586-022-05487-2. Epub 2022 Nov 30. Nature. 2022. Retraction in: Nature. 2025 Aug;644(8075):290. doi: 10.1038/s41586-025-09015-w. PMID: 36450980 Retracted.

References

1. Luo, Z. et al. Multimodal validation of the existence of transitional cerebellar progenitors in the human fetal cerebellum. Preprint at bioRxiv https://doi.org/10.1101/2025.06.01.657310 (2025).

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Retraction Note: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis

Affiliations

Retraction Note: Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis

Authors

Affiliations

Retraction of

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