Lack of evidence for the transitional cerebellar progenitor

Kyle S Smith^#^{1

2}, Yiran Li^#^{1

2}, Parthiv Haldipur³, Brian L Gudenas^{1

2}, Kathleen J Millen³, Volker Hovestadt⁴, Paul A Northcott^{5

6}

Affiliations

¹ Center of Excellence in Neuro-Oncology Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
² Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.
³ Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
⁴ Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA, USA.
⁵ Center of Excellence in Neuro-Oncology Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. paul.northcott@stjude.org.
⁶ Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA. paul.northcott@stjude.org.

^# Contributed equally.

Comment

Kyle S Smith et al. Nature. 2025 Jul.

. 2025 Jul;643(8071):E1-E8.

doi: 10.1038/s41586-025-09247-w. Epub 2025 Jul 9.

Kyle S Smith^#^{1

2}, Yiran Li^#^{1

2}, Parthiv Haldipur³, Brian L Gudenas^{1

2}, Kathleen J Millen³, Volker Hovestadt⁴, Paul A Northcott^{5

6}

¹ Center of Excellence in Neuro-Oncology Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
² Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.
³ Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
⁴ Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA, USA.
⁵ Center of Excellence in Neuro-Oncology Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. paul.northcott@stjude.org.
⁶ Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA. paul.northcott@stjude.org.

^# Contributed equally.

No abstract available

Conflict of interest statement

Competing interests: The authors declare no competing interests.

Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis.
Luo Z, Xia M, Shi W, Zhao C, Wang J, Xin D, Dong X, Xiong Y, Zhang F, Berry K, Ogurek S, Liu X, Rao R, Xing R, Wu LMN, Cui S, Xu L, Lin Y, Ma W, Tian S, Xie Q, Zhang L, Xin M, Wang X, Yue F, Zheng H, Liu Y, Stevenson CB, de Blank P, Perentesis JP, Gilbertson RJ, Li H, Ma J, Zhou W, Taylor MD, Lu QR. Luo Z, et al. Nature. 2022 Dec;612(7941):787-794. doi: 10.1038/s41586-022-05487-2. Epub 2022 Nov 30. Nature. 2022. Retraction in: Nature. 2025 Aug;644(8075):290. doi: 10.1038/s41586-025-09015-w. PMID: 36450980 Retracted.

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