ASO Author Reflections: Toward Better Outcomes in Poorly Differentiated Thyroid Cancer: Evaluating Adjuvant Radiotherapy, Treatment-related Morbidity, and Future Therapeutic Directions

Pascal K C Jonker^{1

2}, Jan H Koetje³, Jia Feng Lin³, Bruce G Robinson^{4

5}, Schelto Kruijff³, Mark S Sywak^{6

4}

Affiliations

¹ University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia. p.k.c.jonker@umcg.nl.
² Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. p.k.c.jonker@umcg.nl.
³ Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
⁴ Department of Endocrinology, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia.
⁵ Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
⁶ University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia.

Pascal K C Jonker et al. Ann Surg Oncol. 2025.

. 2025 Jul 9.

doi: 10.1245/s10434-025-17725-8. Online ahead of print.

Pascal K C Jonker^{1

2}, Jan H Koetje³, Jia Feng Lin³, Bruce G Robinson^{4

5}, Schelto Kruijff³, Mark S Sywak^{6

4}

¹ University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia. p.k.c.jonker@umcg.nl.
² Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. p.k.c.jonker@umcg.nl.
³ Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
⁴ Department of Endocrinology, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia.
⁵ Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
⁶ University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, Australia.

No abstract available

Conflict of interest statement

Declarations. Conflicts of interest: The authors declare no conflicts of interest.

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1. Lee DY, Won JK, Choi HS, et al. Recurrence and Survival After Gross Total Removal of Resectable Undifferentiated or Poorly Differentiated Thyroid Carcinoma. Thyroid. 2016;26(9):1259–68. https://doi.org/10.1089/thy.2016.0147 . - DOI - PubMed
1. Jonker PKC, Koetje JH, Turchini J, et al. Adjuvant External Beam Radiotherapy Reduces Local Recurrence in Poorly Differentiated Thyroid Cancer. Ann Surg Oncol. 2025. https://doi.org/10.1245/s10434-025-17434-2 . - DOI - PubMed
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1. Jonker PKC. De-escalate if possible, intensify when needed: The good, the bad and the ugly: new insights into the full spectrum of thyroid cancer management. Chapter 10; Summary, general discussion and future perspectives. 2025; [Thesis fully internal (DIV), University of Groningen]. University of Groningen. https://doi.org/10.33612/diss.1289645453