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. 1985 Nov;100(11):584-6.

[Effect of immunostimulants on kidney tubule secretion of xenobiotics]

[Article in Russian]
E B Berkhin
  • PMID: 4063508

[Effect of immunostimulants on kidney tubule secretion of xenobiotics]

[Article in Russian]
E B Berkhin. Biull Eksp Biol Med. 1985 Nov.

Abstract

Excretion of cardiotrast (diotrast) was used to study tubular secretion of organic compounds in rats. Immunostimulants prodigiosin (0.05 mg/kg) and levamisole (10 mg/kg) injected subcutaneously three times every other day increased cardiotrast excretion. High levamisole dose (50 mg/kg), having no stimulating effect on the immunity, failed also to influence tubular cardiotrast transport. Possible mechanisms of immunostimulants' action on the tubular secretion of xenobiotics is discussed.

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