Conflict of Interest Disclosures: Dr Alexeeff reported receiving grants from National Institutes of Health during the conduct of the study. Dr Ambrosy reported receiving grants to his institution from the National Heart, Lung, and Blood Institute (K23HL150159 and R01AG091005), the American Heart Association (2nd Century Early Faculty Independence Award), The Permanente Medical Group, Kaiser Permanente Northern California Community Benefits Programs, Garfield Memorial Fund, Abbott Laboratories, Amarin Pharma, Inc, Bayer Pharma AG, Cordio Medical, Edwards Lifesciences LLC, Esperion Therapeutics, Inc, Merck, and Novartis and has been a consultant to Corstasis, Merck, Novo Nordisk, and scPharma. Dr Daida reported receiving grants from Gilead Sciences, Sanofi, and Vir Biotechnology outside the submitted work. Dr Go reported receiving grants from National Heart, Lung, and Blood Institute during the conduct of the study and grants from Bristol Myers Squibb and Novartis through the institution outside the submitted work. No other disclosures were reported.