NCCN Guidelines® Insights: Thyroid Carcinoma, Version 1.2025

Robert I Haddad¹, Lindsay Bischoff², Megan Applewhite³, Victor Bernet⁴, Erik Blomain⁵, Maria Brito⁶, Naifa Lamki Busaidy⁷, Michael Campbell⁸, Olivia DeLozier⁹, Quan-Yang Duh¹⁰, Hormoz Ehya¹¹, Erin Grady⁵, Theresa Guo¹², Megan Haymart¹³, Jason P Hunt¹⁴, Fouad Kandeel¹⁵, Anupam Kotwal¹⁶, Dominick M Lamonica¹⁷, Jochen Lorch¹⁸, Susan J Mandel¹⁹, Stephanie Markovina²⁰, Wojciech Mydlarz²¹, Lisle Nabell²², Christopher D Raeburn²³, Rod Rezaee²⁴, John A Ridge¹¹, Hadley Ritter²⁵, Mara Y Roth²⁶, Sarimar Agosto Salgado²⁷, Randall P Scheri²⁸, Jatin P Shah²⁹, Jennifer A Sipos³⁰, Rebecca Sippel³¹, Cord Sturgeon¹⁸, Lori J Wirth¹, Richard J Wong²⁹, Francis Worden¹³, Michael W Yeh³², Susan Darlow³³, Carly J Cassara³³, Bailee Sliker³³

Affiliations

¹ 1Dana-Farber/Brigham and Women's Cancer Center | Mass General Cancer Center.
² 2Vanderbilt-Ingram Cancer Center.
³ 3The UChicago Medicine Comprehensive Cancer Center.
⁴ 4Mayo Clinic Comprehensive Cancer Center.
⁵ 5Stanford Cancer Institute.
⁶ 6UT Southwestern Simmons Comprehensive Cancer Center.
⁷ 7The University of Texas MD Anderson Cancer Center.
⁸ 8UC Davis Comprehensive Cancer Center.
⁹ 9St. Jude Children's Research Hospital/The University of Tennessee Health Science Center.
¹⁰ 10UCSF Helen Diller Family Comprehensive Cancer Center.
¹¹ 11Fox Chase Cancer Center.
¹² 12UC San Diego Moores Cancer Center.
¹³ 13University of Michigan Rogel Cancer Center.
¹⁴ 14Huntsman Cancer Institute at the University of Utah.
¹⁵ 15City of Hope National Medical Center.
¹⁶ 16Fred & Pamela Buffett Cancer Center.
¹⁷ 17Roswell Park Comprehensive Cancer Center.
¹⁸ 18Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
¹⁹ 19Abramson Cancer Center at the University of Pennsylvania.
²⁰ 20Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
²¹ 21Johns Hopkins Kimmel Cancer Center.
²² 22O'Neal Comprehensive Cancer Center at UAB.
²³ 23University of Colorado Cancer Center.
²⁴ 24Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
²⁵ 25Indiana University Melvin and Bren Simon Comprehensive Cancer Center.
²⁶ 26Fred Hutchinson Cancer Center.
²⁷ 27Moffitt Cancer Center.
²⁸ 28Duke Cancer Institute.
²⁹ 29Memorial Sloan Kettering Cancer Center.
³⁰ 30The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
³¹ 31University of Wisconsin Carbone Cancer Center.
³² 32UCLA Jonsson Comprehensive Cancer Center.
³³ 33National Comprehensive Cancer Network.

PMID: 40639400
DOI: 10.6004/jnccn.2025.0033

Practice Guideline

NCCN Guidelines® Insights: Thyroid Carcinoma, Version 1.2025

Robert I Haddad et al. J Natl Compr Canc Netw. 2025 Jul.

. 2025 Jul;23(7):e250033.

doi: 10.6004/jnccn.2025.0033.

Authors

Affiliations

¹ 1Dana-Farber/Brigham and Women's Cancer Center | Mass General Cancer Center.
² 2Vanderbilt-Ingram Cancer Center.
³ 3The UChicago Medicine Comprehensive Cancer Center.
⁴ 4Mayo Clinic Comprehensive Cancer Center.
⁵ 5Stanford Cancer Institute.
⁶ 6UT Southwestern Simmons Comprehensive Cancer Center.
⁷ 7The University of Texas MD Anderson Cancer Center.
⁸ 8UC Davis Comprehensive Cancer Center.
⁹ 9St. Jude Children's Research Hospital/The University of Tennessee Health Science Center.
¹⁰ 10UCSF Helen Diller Family Comprehensive Cancer Center.
¹¹ 11Fox Chase Cancer Center.
¹² 12UC San Diego Moores Cancer Center.
¹³ 13University of Michigan Rogel Cancer Center.
¹⁴ 14Huntsman Cancer Institute at the University of Utah.
¹⁵ 15City of Hope National Medical Center.
¹⁶ 16Fred & Pamela Buffett Cancer Center.
¹⁷ 17Roswell Park Comprehensive Cancer Center.
¹⁸ 18Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
¹⁹ 19Abramson Cancer Center at the University of Pennsylvania.
²⁰ 20Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
²¹ 21Johns Hopkins Kimmel Cancer Center.
²² 22O'Neal Comprehensive Cancer Center at UAB.
²³ 23University of Colorado Cancer Center.
²⁴ 24Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
²⁵ 25Indiana University Melvin and Bren Simon Comprehensive Cancer Center.
²⁶ 26Fred Hutchinson Cancer Center.
²⁷ 27Moffitt Cancer Center.
²⁸ 28Duke Cancer Institute.
²⁹ 29Memorial Sloan Kettering Cancer Center.
³⁰ 30The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
³¹ 31University of Wisconsin Carbone Cancer Center.
³² 32UCLA Jonsson Comprehensive Cancer Center.
³³ 33National Comprehensive Cancer Network.

PMID: 40639400
DOI: 10.6004/jnccn.2025.0033

Abstract

The NCCN Guidelines for Thyroid Carcinoma address the management of different types of thyroid carcinoma, including papillary, follicular, oncocytic, medullary, and anaplastic carcinoma. The NCCN Thyroid Carcinoma Panel meets at least annually to review comments from reviewers within their institutions, examine relevant new data from publications and abstracts, and reevaluate and update their recommendations. These NCCN Guidelines Insights focus on the panel's most recent recommendations regarding systemic therapies for thyroid carcinoma as well as the supporting clinical data.

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NCCN Guidelines® Insights: Thyroid Carcinoma, Version 1.2025

Affiliations

NCCN Guidelines® Insights: Thyroid Carcinoma, Version 1.2025

Authors

Affiliations

Abstract

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical