Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jul 10;8(1):427.
doi: 10.1038/s41746-025-01836-3.

A scoping review of the governance of federated learning in healthcare

Affiliations

A scoping review of the governance of federated learning in healthcare

Rebekah Eden et al. NPJ Digit Med. .

Abstract

In healthcare, federated learning (FL) is emerging as a methodology to enable the analysis of large and disparate datasets while allowing custodians to retain sovereignty. While FL minimises data-sharing challenges, concerns surrounding ethics, privacy, maleficent use, and harm remain. These concerns can be managed by effective data governance. Data governance specifies procedural, relational, and structural mechanisms governing how data is captured, shared, and analysed, the resultant models and their use. However, limited insights exist on the optimal governance of this emerging technology. This study aims to develop a consolidated framework of the data governance mechanisms for FL in healthcare. A scoping review was performed, using deductive and inductive analysis of 39 articles. The framework includes twelve procedural, ten relational, and twelve structural mechanisms. The framework directs researchers to examine how to enact each mechanism and provides practitioners with insights into the mechanism to consider when governing FL.

PubMed Disclaimer

Conflict of interest statement

Competing interests: Anthony Nguyen is an Associate Editor of npj Digital Medicine. The other authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Article screening and selection process.
The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagram detailing the article screening process.
Fig. 2
Fig. 2. Procedural, relational, and structural mechanisms necessary to govern FL.
Note: asterisk (*) denotes that the mechanism has yet to be explicitly reported in FL papers but are apparent in FDN/ML papers. Future research is necessary to identify their relevance and how they can be tailored to FL.

References

    1. Friedman, C. et al. Toward a science of learning systems: a research agenda for the high-functioning Learning Health System. J. Am. Med. Inform. Assoc.22, 43–50 (2015). - PMC - PubMed
    1. Platt, J. E., Raj, M. & Wienroth, M. An analysis of the learning health system in its first decade in practice: scoping review. J. Med. Internet Res.22, e17026 (2020). - PMC - PubMed
    1. Syed, R. et al. Digital health data quality issues: systematic review. J. Med. Internet Res.25, e42615 (2023). - PMC - PubMed
    1. Austin, J. A. et al. Decades in the Making: The Evolution of Digital Health Research Infrastructure Through Synthetic Data, Common Data Models, and Federated Learning. J. Med. Internet Res.26, e58637 (2024). - PMC - PubMed
    1. Rieke, N. et al. The future of digital health with federated learning. npj Digital Med.3, 119 (2020). - PMC - PubMed

LinkOut - more resources