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Editorial
. 2025 Jul;30(7):e70078.
doi: 10.1111/nep.70078.

Are Your Kidneys Ok? Detect Early to Protect Kidney Health

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Editorial

Are Your Kidneys Ok? Detect Early to Protect Kidney Health

Joseph A Vassalotti et al. Nephrology (Carlton). 2025 Jul.

Abstract

Early identification of kidney disease can protect kidney health, prevent kidney disease progression and related complications, reduce cardiovascular disease (CVD) risk and decrease mortality. We must ask 'Are your kidneys ok?' using serum creatinine to estimate kidney function and urine albumin to assess for kidney and endothelial damage. Evaluation for causes and risk factors for chronic kidney disease (CKD) includes testing for diabetes and measurement of blood pressure and body mass index. This World Kidney Day, we assert that case-finding in high-risk populations, or even population-level screening, can decrease the burden of kidney disease globally. Early-stage CKD is asymptomatic, simple to test for and recent paradigm-shifting CKD treatments, such as sodium glucose co-transporter-2 inhibitors, dramatically improve outcomes and favour the cost-benefit analysis for screening or case-finding programmes. Despite this, numerous barriers exist, including resource allocation, healthcare funding, healthcare infrastructure and healthcare-professional and population awareness of kidney disease. Coordinated efforts by major kidney non-governmental organisations to prioritise the kidney health agenda for governments and aligning early detection efforts with other current programmes will maximise efficiencies.

Keywords: albuminuria; case finding; chronic kidney disease; prevention; proteinuria; screening.

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References

    1. C. E. Ndumele, I. J. Neeland, K. R. Tuttle, et al., “A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular‐Kidney‐Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association,” Circulation 148, no. 20 (2023): 1636–1664.
    1. V. A. Luyckx, K. R. Tuttle, D. Abdellatif, et al., “Mind the Gap in Kidney Care: Translating What We Know Into What We Do,” Kidney International 105, no. 3 (2024): 406–417.
    1. P. E. Stevens, S. B. Ahmed, J. J. Carrero, et al., “KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease,” Kidney International 105, no. 4 (2024): S117–S314.
    1. C. Guha, P. Lopez‐Vargas, A. Ju, et al., “Patient Needs and Priorities for Patient Navigator Programmes in Chronic Kidney Disease: A Workshop Report,” BMJ Open 10, no. 11 (2020): e040617.
    1. Collaboration GBDCKD, “Global, Regional, and National Burden of Chronic Kidney Disease, 1990‐2017: A Systematic Analysis for the Global Burden of Disease Study 2017,” Lancet 395, no. 10225 (2020): 709–733.

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