Elevated Levels of Extracellular Vesicle-Associated TAOK1 in Plasma: A Diagnostic Marker for Cognitive Decline in Parkinson's Disease Dementia and Alzheimer's Disease

Pin-Jui Kung¹, Yi-Tzang Tsai², Rwei-Ling Yu³, Hsiang-Hsuan Lin-Wang², Ming-Che Kuo^{4

5}, Chia-Ching Wu⁶, Chien-Tai Hong^{7

8}, Koji Ueda⁹, Shau-Ping Lin^{1

2

10

11}, Ruey-Meei Wu^{4

12}

Affiliations

¹ Genome and Systems Biology Degree Program, National Taiwan University and Academia Sinica, Taipei, Taiwan.
² Institute of Biotechnology, National Taiwan University, Taipei, Taiwan.
³ Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁴ Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
⁵ Department of Medicine, National Taiwan University Cancer Center, Taipei, Taiwan.
⁶ Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁷ Department of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
⁸ Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
⁹ Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan.
¹⁰ Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan.
¹¹ Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.
¹² Department of Neurology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

Pin-Jui Kung et al. Mov Disord. 2025.

. 2025 Jul 11.

doi: 10.1002/mds.30287. Online ahead of print.

¹ Genome and Systems Biology Degree Program, National Taiwan University and Academia Sinica, Taipei, Taiwan.
² Institute of Biotechnology, National Taiwan University, Taipei, Taiwan.
³ Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁴ Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
⁵ Department of Medicine, National Taiwan University Cancer Center, Taipei, Taiwan.
⁶ Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
⁷ Department of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
⁸ Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
⁹ Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan.
¹⁰ Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan.
¹¹ Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.
¹² Department of Neurology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

No abstract available

Publication types