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Case Reports
. 2025 May 3:31:52-57.
doi: 10.1016/j.xjtc.2025.04.016. eCollection 2025 Jun.

Autologous leaflet reconstruction for aortic valve endocarditis

Timothy W James  1 , J Hunter Mehaffey  2 , Vinay Badhwar  2 , J Scott Rankin  2
Affiliations
Case Reports

Autologous leaflet reconstruction for aortic valve endocarditis

Timothy W James et al. JTCVS Tech. .
No abstract available

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Conflict of interest statement

Dr Rankin previously was a consultant for BioStable Science and Engineering. All other authors reported no conflicts of interest. The Journal policy requires editors and reviewers to disclose conflicts of interest and to decline handling or reviewing manuscripts for which they may have a conflict of interest. The editors and reviewers of this article have no conflicts of interest.

Figures

None
Suturing a leaflet of autologous aortic wall to the right annulus for endocarditis repair.
Figure 1
Figure 1
Techniques of analysis used to design replacement leaflets. A, Raw 3-dimensional data points for all 3 leaflets. B, Leaflet geometry defined by ellipsoidal regression with coaptation zones removed. C, Single leaflet data points compared to regression geometry. D, Development of 2-dimensional single leaflet templates from emperic data. See text for details. FEL, Free-edge length; GH, geometric height.
Figure 2
Figure 2
Surgical stainless-steel leaflet templates used to construct neoleaflets of aortic wall for annular/leaflet sizes 17 to 27 mm. Templates were fabricated by Centex Machining, Inc.
Figure 3
Figure 3
A, Prerepair echocardiogram showing severe AI. B, Prerepair pathology with a perforation in the noncoronary leaflet (red arrow) and an absent right coronary leaflet (green arrow). C, Postrepair echocardiogram showing no AI. D, Good matching and coaptation of the neoright coronary leaflet of aortic wall with the other native leaflets. AI, Aortic insufficiency.
See this image and copyright information in PMC

References

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E-References

    1. Burkhart H.M., Nakamura Y., Mir A., Badhwar V., Rankin J.S. Upsized ring annuloplasty an autologous leaflet augmentation: a new paradigm for pediatric aortic valve repair. J Thorac Cardiovasc Surg Tech. 2024;27:135–137. - PMC - PubMed
    1. James T.W., Mehaffey J.H., Wei L.M., Voeller R.K., Badhwar V., Rankin J.S. Repair of calcified bicuspid aortic valves using living autologous aortic wall leaflets. J Thorac Cardiovasc Surg Tech. 2024;25:48–51. - PMC - PubMed
    1. Nissen A.P., Levack M.M., Badhwar V., Rankin J.S., Keeling W.B. Aortic valve repair for severe commissural leaflet defects using aortic wall patches. Ann Thorac Surg Short Rep. 2025 Published online February 25, 2025.
    1. Rankin J.S., James T.W., Burkhart H.M., et al. Use of autologous aortic wall for leaflet replacement during aortic valve repair. CTSNet.org. 2024. https://www.ctsnet.org/article/use-autologous-aortic-wall-leaflet-replac...
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