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. 2025 Jul 9;13(2):e70020.
doi: 10.1002/anr3.70020. eCollection 2025 Jul-Dec.

Postoperative bilateral visual loss after a single dose of tranexamic acid

B Chevalley  1 , M Betello  1 , E Blavakis  2 , A Malclès  2   3 , J Maillard  1
Affiliations

Postoperative bilateral visual loss after a single dose of tranexamic acid

B Chevalley et al. Anaesth Rep. .

Abstract

A 32-year-old woman presented with transient visual loss following the intra-operative administration of a single intravenous dose of tranexamic acid during urgent cholecystectomy. Apart from obesity, the patient had no notable medical history or pre-existing ocular conditions. Immediately after surgery, the patient reported sudden onset blindness. Ophthalmological and radiologic assessments did not reveal any detectable macrovascular or organic ophthalmic lesions. The patient's vision gradually improved spontaneously, with the resolution of the dyschromatopsia on the first postoperative day and complete recovery by the second postoperative day. This case highlights the importance of prompt investigation of acute visual impairment postoperatively and identifying potential causative agents, such as tranexamic acid.

Keywords: postoperative visual loss; tranexamic acid; visual disturbance.

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References

    1. Roth S. Perioperative visual loss: what do we know, what can we do? Br J Anaesth 2009; 103: i31–i40. - PMC - PubMed
    1. Wijetilleka S, Yeo DCM, Sharma B. Central retinal artery occlusion in a 30‐year‐old woman taking tranexamic acid. BMJ Case Rep 2017; 2017: bcr‐2016‐218246. - PMC - PubMed
    1. Al Shaharani AM, Al Ghamdi TA. Central retinal vein occlusion associated with the use of tranexamic acid. Saudi J Ophthalmol 2020; 34: 148–150. - PMC - PubMed
    1. Luo R, Lu L, You Y. Perioperative vision loss after sequential lower extremity fracture surgery: a case report. J Int Med Res 2024; 52: 03000605241300048. - PMC - PubMed
    1. Reed MR, Woolley LT. Uses of tranexamic acid. Contin Educ Anaesth Crit Care Pain 2015; 15: 32–37.

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