Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 Jun 19:61:103098.
doi: 10.1016/j.eucr.2025.103098. eCollection 2025 Jul.

Prostate-sparing conservative management of a solitary fibrous tumor of the prostate: A case report

Ludovica Cella  1   2 , Beatrice Gatti  1   3 , Salvatore Renne  1   3 , Ferdinando Cananzi  1   4 , Giuseppe Ferrillo  5 , Paolo Casale  2 , Pier Giuseppe Colombo  1   3 , Giovanni Lughezzani  1   2
Affiliations
Case Reports

Prostate-sparing conservative management of a solitary fibrous tumor of the prostate: A case report

Ludovica Cella et al. Urol Case Rep. .

Abstract

Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms with variable malignancy potential. We report a 69-year-old man with elevated PSA and an asymptomatic pelvic solid mass (42 × 32 × 48 mm), found on imaging between the bladder and anterior prostate. CT-guided biopsy confirmed an intermediate/low-risk SFT per WHO 2020. The lesion was successfully removed via robotic prostate-sparing surgery. Accurate histopathological diagnosis is key to avoid overtreatment, as SFTs can mimic more aggressive tumors. Complete excision offers good prognosis, though long-term follow-up is warranted due to potential for recurrence or progression.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Axial abdomen CT scan.
Fig. 2
Fig. 2
Axial (a) and sagittal (b) abdominal MRI scan.
Fig. 3
Fig. 3
A: Hematoxylin-Eosin, scalebar 50 μm; B: STAT6, positive, scalebar 50 μm; C:CD34, strongly positive, scalebar 50 μm; D: DOG1, negative, scalebar 50 μm.
Fig. 4
Fig. 4
SFT specimen, showing the adhesion of the tumour (asterisk) with the prostatic capsule adjacent to the prostatic glands (arrowhead). Hematoxylin and Eosin, scalebar indicates 500 μm.
See this image and copyright information in PMC

References

    1. de Pinieux G., Karanian M., Le Loarer F., et al. Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network. PLoS One. 2021;16(2) doi: 10.1371/journal.pone.0246958. - DOI - PMC - PubMed
    1. Pasquali S., Gronchi A., Strauss D., et al. Resectable extra-pleural and extra-meningeal solitary fibrous tumours: a multi-centre prognostic study. Eur J Surg Oncol. 2016;42(7):1064–1070. doi: 10.1016/j.ejso.2016.01.023. - DOI - PubMed
    1. Gholami S., Cassidy M.R., Kirane A., et al. Size and location are the Most important risk factors for malignant behavior in resected solitary fibrous tumors. Ann Surg Oncol. 2017;24(13):3865–3871. doi: 10.1245/s10434-017-6092-z. - DOI - PubMed
    1. Gronchi A., Miah A.B., Dei Tos AP., et al. Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2021;32(11):1348–1365. doi: 10.1016/j.annonc.2021.07.006. - DOI - PubMed
    1. Demicco E.G., Park M.S., Araujo D.M., et al. Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model. Mod Pathol. 2012;25(9):1298–1306. doi: 10.1038/modpathol.2012.83. - DOI - PubMed

Publication types

LinkOut - more resources