Comparative Study
doi: 10.1007/BF01950011.
Comparison of the effects of different isomers of bicuculline infused in the preoptic area on male rat sexual behavior
- PMID: 4065295
- DOI: 10.1007/BF01950011
Item in Clipboard
Comparative Study
Comparison of the effects of different isomers of bicuculline infused in the preoptic area on male rat sexual behavior
Experientia.
.
Abstract
Intracerebral infusion of (+) bicuculline methiodide, but not of its (-) isomer, in the preoptic area, stimulated masculine sexual behavior in rat as evidenced by a decrease in the number of intromissions preceding ejaculation and a shortening of the ejaculation latency and postejaculatory interval. Data suggest a role of the GABAergic system in mediating masculine sexual behavior.
Similar articles
-
GABAergic control of masculine sexual behavior.Pharmacol Biochem Behav. 1986 Apr;24(4):1065-70. doi: 10.1016/0091-3057(86)90456-9. Pharmacol Biochem Behav. 1986. PMID: 3012591
-
Depression of postejaculatory ultrasonic vocalization by (+)-bicuculline.Behav Brain Res. 1986 Jan;19(1):35-9. doi: 10.1016/0166-4328(86)90045-8. Behav Brain Res. 1986. PMID: 3954865
-
Facilitation of sexual behavior shortly after electrolytic lesion of the medial preoptic area: what does it mean?Brain Res Bull. 1992 Jul;29(1):125-8. doi: 10.1016/0361-9230(92)90016-q. Brain Res Bull. 1992. PMID: 1504848
-
The sexually dimorphic medial preoptic nucleus of quail: a key brain area mediating steroid action on male sexual behavior.Front Neuroendocrinol. 1996 Jan;17(1):51-125. doi: 10.1006/frne.1996.0002. Front Neuroendocrinol. 1996. PMID: 8788569 Review.
-
Pharmacological and physiological aspects of sexual exhaustion in male rats.Scand J Psychol. 2003 Jul;44(3):257-63. doi: 10.1111/1467-9450.00343. Scand J Psychol. 2003. PMID: 12914589 Review.
Cited by
-
Steroid and barbiturate modulation of the GABAa receptor. Possible mechanisms.Mol Neurobiol. 1989 Winter;3(4):275-304. doi: 10.1007/BF02740608. Mol Neurobiol. 1989. PMID: 2560920 Review.
-
Altered GABAA receptor-mediated synaptic transmission disrupts the firing of gonadotropin-releasing hormone neurons in male mice under conditions that mimic steroid abuse.J Neurosci. 2010 May 12;30(19):6497-506. doi: 10.1523/JNEUROSCI.5383-09.2010. J Neurosci. 2010. PMID: 20463213 Free PMC article.