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Comparative Study
. 1985 Nov 15;41(11):1414-6.
doi: 10.1007/BF01950011.

Comparison of the effects of different isomers of bicuculline infused in the preoptic area on male rat sexual behavior

A Fernández-Guasti, K Larsson, C Beyer
Comparative Study

Comparison of the effects of different isomers of bicuculline infused in the preoptic area on male rat sexual behavior

A Fernández-Guasti et al. Experientia. .

Abstract

Intracerebral infusion of (+) bicuculline methiodide, but not of its (-) isomer, in the preoptic area, stimulated masculine sexual behavior in rat as evidenced by a decrease in the number of intromissions preceding ejaculation and a shortening of the ejaculation latency and postejaculatory interval. Data suggest a role of the GABAergic system in mediating masculine sexual behavior.

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