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Review
. 2025 Oct:192:171428.
doi: 10.1016/j.peptides.2025.171428. Epub 2025 Jul 11.

Maximizing cost savings in heart failure management: The economic value of natriuretic peptide testing

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Review

Maximizing cost savings in heart failure management: The economic value of natriuretic peptide testing

Damien Gruson et al. Peptides. 2025 Oct.

Abstract

Heart failure (HF) remains a significant global health challenge, requiring cost-effective strategies to optimize patient outcomes and resource allocation. Natriuretic peptide (NP) testing has demonstrated substantial clinical and economic value in HF diagnosis, risk stratification, and management. This article examines the international evidence supporting NP testing, highlighting its role in reducing hospitalizations, optimizing medication use, and lowering healthcare expenditures. Addressing disparities in access and reimbursement policies can further enhance its adoption and impact across healthcare systems.

Keywords: Biomarker testing; Cost-effectiveness; Healthcare economics; Heart failure; NT-proBNP; Natriuretic peptides.

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Conflict of interest statement

Declaration of Competing Interest The authors declare no conflict of interest.

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