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. 1985 Dec 2;193(2):250-4.
doi: 10.1016/0014-5793(85)80163-0.

Amino acid sequence of heat-stable enterotoxin produced by Vibrio cholerae non-01

T Takao, Y Shimonishi, M Kobayashi, O Nishimura, M Arita, T Takeda, T Honda, T Miwatani
Free article

Amino acid sequence of heat-stable enterotoxin produced by Vibrio cholerae non-01

T Takao et al. FEBS Lett. .
Free article

Abstract

The amino acid sequence of heat-stable enterotoxin, produced by Vibrio cholerae non-01 and isolated from its culture supernatant, was determined by both Edman degradation of native and reductively carboxymethylated enterotoxin and also a combination of fast atom bombardment mass spectrometry and carboxypeptidase Y digestion of native enterotoxin to be as follows: Ile-Asp-Cys-Cys-Glu-Ile-Cys-Cys-Asn-Pro-Ala-Cys-Phe-Gly-Cys-Leu-Asn. This sequence is very similar, but not identical, to those of heat-stable enterotoxins produced by enterotoxigenic Escherichia coli and Yersinia enterocolitica.

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