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Case Reports
. 2025 Jul 1:2025:2537488.
doi: 10.1155/cria/2537488. eCollection 2025.

Infant Spinal Anesthesia for Urologic Surgery in a Patient With Epidermolysis Bullosa

Alexander B Froyshteter  1 , Jillian A Dibiase  1 , Catherine M Seager  2 , Alina Lazar  1
Affiliations
Case Reports

Infant Spinal Anesthesia for Urologic Surgery in a Patient With Epidermolysis Bullosa

Alexander B Froyshteter et al. Case Rep Anesthesiol. .

Abstract

Infant spinal anesthesia presents a viable alternative to general anesthesia for short procedures below the umbilicus. This technique eliminates the need for airway instrumentation while preserving hemodynamic and respiratory parameters. Epidermolysis bullosa is a rare inherited genetic disorder marked by mucocutaneous fragility, erosions, ulcerations, and blister formation. Anesthesia management for patients with epidermolysis bullosa necessitates meticulous planning to minimize shearing stress on the skin and mucosa. This case report details the application of spinal anesthesia for an infant with epidermolysis bullosa for urologic surgery, highlighting special considerations for neuraxial block placement in this vulnerable population.

Keywords: epidermolysis bullosa; infant; spinal anesthesia.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Patient with epidermolysis bullosa showing extensive ulcerations and blistering.
Figure 2
Figure 2
Patient positioned lateral decubitus prior to spinal block.
Figure 3
Figure 3
Patient asleep with natural airway during procedure done under spinal anesthesia.
See this image and copyright information in PMC

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References

    1. Hon K. L., Chu S., Leung A. K. C. Epidermolysis Bullosa: Pediatric Perspectives. Current Pediatric Reviews . 2022;18(3):182–190. doi: 10.2174/1573396317666210525161252. - DOI - PubMed
    1. Bardhan A., Bruckner-Tuderman L., Chapple I. L. C., et al. Epidermolysis Bullosa. Nature Reviews Disease Primers . 2020;6(1):p. 78. doi: 10.1038/s41572-020-0210-0. - DOI - PubMed
    1. Sprecher E. Epidermolysis Bullosa Simplex. Dermatologic Clinics . 2010;28(1):23–32. doi: 10.1016/j.det.2009.10.003. - DOI - PubMed
    1. Mittal B. M., Goodnough C. L., Bushell E., Turkmani-Bazzi S., Sheppard K. Anesthetic Management of Adults with Epidermolysis Bullosa. Anesthesia & Analgesia . 2022;134(1):90–101. doi: 10.1213/ane.0000000000005706. - DOI - PMC - PubMed
    1. Bowen L., Burtonwood M. T. Anaesthetic Management of Children with Epidermolysis Bullosa. BJA Education . 2018;18(2):41–45. doi: 10.1016/j.bjae.2017.11.005. - DOI - PMC - PubMed

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