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Review
. 2025 Jul 14;27(1):52.
doi: 10.1007/s11894-025-00990-8.

Practical Tips for Diagnosis and Management of Concomitant Inflammatory Spondyloarthritis and Inflammatory Bowel Disease

Katherine Falloon  1 , Michael Forney  2 , Shashank Cheemalavagu  3 , M Elaine Husni  4 , Florian Rieder  5   6   7
Affiliations
Review

Practical Tips for Diagnosis and Management of Concomitant Inflammatory Spondyloarthritis and Inflammatory Bowel Disease

Katherine Falloon et al. Curr Gastroenterol Rep. .

Abstract

Purpose of review: The goal of this review is to provide practical guidance for gastroenterologists regarding diagnosis and management of inflammatory bowel disease associated spondyloarthritis.

Recent findings: While there is limited data regarding optimal management approaches, we summarize available screening tools along with classification and consensus criteria that can be deployed in this setting and offer guidance regarding patient symptoms, physical exam findings, laboratory data, and imaging strategies that may facilitate diagnosis. In addition, we outline various therapeutic options available while highlighting deficits in the currently available literature. Inflammatory bowel disease associated spondyloarthritis is common but remains poorly understood. Ongoing research to establish a clear diagnostic pathway and reproducible treatment targets is essential to better identify and treat this patient population.

Keywords: Axial arthritis; Crohn’s disease; Inflammatory arthritis; Inflammatory bowel disease; Spondyloarthritis; Ulcerative colitis.

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Conflict of interest statement

Declarations. Ethical Approval: All reported studies/experiments with human or animal subjects performed by the authors have been previously published and complied with all applicable ethical standards (including the Helsinki declaration and its amendments, institutional/national research committee standards, and international/national/institutional guidelines). Competing Interests: KF receives grant funding from the Crohn’s and Colitis Foundation (916943) and Pfizer (90146787). She served on an advisory panel for Janssen. MF consultant for BD Peripheral Vascular (Tempe, AZ) and Siemens Ultrasound (Issaquah, Washington). SC has no disclosures MEH consultant to Abbvie, BMS, Novartis, Eli Lilly, Janssen, and UCB, co-inventor PASE questionnaire receives royalties. Grant funded from the Arthritis Foundation and National Psoriasis Foundation and NIH. FR is a consultant to Adiso, Adnovate, Agomab, Allergan, AbbVie, Arena, Astra Zeneca, Bausch & Lomb, Boehringer-Ingelheim, Celgene/BMS, Celltrion, CDISC, Celsius, Cowen, Eugit, Ferring, Galapagos, Galmed, Genentech, Gilead, Gossamer, Granite, Guidepoint, Helmsley, Horizon Therapeutics, Image Analysis Limited, Index Pharma, Landos, Jannsen, Koutif, Mestag, Metacrine, Mirum, Mopac, Morphic, Myka Labs, Organovo, Origo, Palisade, Pfizer, Pliant, Prometheus Biosciences, Receptos, RedX, Roche, Samsung, Sanofi, Surmodics, Surrozen, Takeda, Techlab, Teva, Theravance, Thetis, Trix Bio, UCB, Ysios, 89Bio.

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