Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Aug;194(4):1517-1524.
doi: 10.1007/s11845-025-04004-4. Epub 2025 Jul 14.

Ultrasound evaluation of muscles in older patients with metabolıc syndrome

Ibrahim Ileri  1 , Merve Hafizoglu  2 , Didem Karaduman  2 , Cansu Atbas  2 , Zeynep Sahiner  2 , Ayse Dikmeer  2 , Yelda Ozturk  2 , Merve Guner  2 , Arzu Okyar Bas  2 , Cafer Balci  2 , Mustafa Cankurtaran  2 , Burcu Balam Dogu  2 , Meltem Gülhan Halil  2
Affiliations

Ultrasound evaluation of muscles in older patients with metabolıc syndrome

Ibrahim Ileri et al. Ir J Med Sci. 2025 Aug.

Abstract

Background: Metabolic syndrome (MetS) is a disease characterized by various metabolic disorders and increases the risk of cardiovascular events. Osteosarcopenia (OS) is the name given to conditions where osteopenia/osteoporosis (OP) and sarcopenia coexist. In this study, the relationship between MetS and bones assessed by dual-energy X-ray absorptiometry (DXA) and muscles assessed by muscle ultrasonography (USG) was investigated.

Methods: The study conducted among patients aged 65 and over who applied to the geriatric outpatient clinic between January 2022 and June 2022. This study was a cross-sectional study. There were 161 patients.

Results: In the study, 77 (73%) of the patients with MetS were female and the median age of the patients with MetS was 72(9) interquartile range (IQR) years. While OP was present in 18% of patients with MetS, this rate was 41% in those without MetS, and this difference was significant (p = 0.002). There was no difference in OS and sarcopenia rates between the two groups (respectively; p = 0.14, p = 0.09). Gastrocnemius medialis (GM) and transversus abdominis (TA) muscles were significantly thicker in patients with MetS (respectively; p = 0.002, p = 0.003).

Keywords: Metabolic syndrome; Muscles; Older patients; Sarcopenia; Ultrasonography.

PubMed Disclaimer

Conflict of interest statement

Declarations. Support: None. Financial Disclosure: The authors declare that they have no relevant financial interests. Conflict of interest: The authors declare that they have no conflict of interest.

References

    1. Jenkins TA (2022) Metabolic syndrome and vascular-associated cognitive impairment: a focus on preclinical investigations. Curr Diab Rep 22:333–340. https://doi.org/10.1007/s11892-022-01475-y - DOI - PubMed - PMC
    1. Alkhulaifi F, Darkoh C (2022) Meal timing, meal frequency and metabolic syndrome. Nutrients 14:1719. https://doi.org/10.3390/nu14091719 - DOI - PubMed - PMC
    1. Fahed G, Aoun L, Zerdan MB and others (2022) Metabolic syndrome: Updates on pathophysiology and management in 2021. Int J Mol Sci 23:786. https://doi.org/10.3390/ijms23020786 - DOI - PubMed - PMC
    1. Azimi-Nezhad M, Aminisani N, Ghasemi A and others (2022) Sex-specific prevalence of metabolic syndrome in older adults: results from the Neyshabur longitudinal study on aging Iran. J Diabetes Metab Disord 21:263–273. https://doi.org/10.1007/s40200-022-00969-6 - DOI - PubMed - PMC
    1. Johnston CB, Dagar M (2020) Osteoporosis in older adults. Med Clin North Am 104:873–884. https://doi.org/10.1016/j.mcna.2020.06.004 - DOI - PubMed

LinkOut - more resources