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Review
. 2026 Jan;55(1):1-17.
doi: 10.1007/s00256-025-04978-3. Epub 2025 Jul 15.

Distal tibiofibular syndesmotic instability: revisiting essential concepts and clarifying advanced imaging tests

Affiliations
Review

Distal tibiofibular syndesmotic instability: revisiting essential concepts and clarifying advanced imaging tests

João Carlos Rodrigues et al. Skeletal Radiol. 2026 Jan.

Abstract

Most acute ankle sprains involve injuries to the lateral collateral ligaments, while a smaller proportion pertain to injuries of the deltoid ligament or the distal tibiofibular syndesmosis ligaments. Despite being less common, syndesmotic injuries can lead to persistent symptoms, extended recovery periods, and more intricate treatment protocols compared to lateral collateral ligament injuries. In the decision-making process for treating syndesmotic injuries, evaluating both ligament tears and the degree of joint instability is essential, as the latter determines whether a patient should be treated conservatively or surgically. Imaging has an established role in diagnosing syndesmotic ligament injuries; however, conventional imaging techniques have limitations in assessing instability. In this qualitative review, the authors discuss the anatomy and biomechanics, along with a review of current imaging techniques for evaluating syndesmotic instability. By clarifying imaging strategies, comparing diagnostic methods, and introducing emerging techniques, this review serves as a valuable resource for radiologists aiming to expand their knowledge of syndesmotic instability, particularly in cases that may be subtle and often missed on routine studies.

Keywords: Diagnostic imaging; High ankle sprain; Syndesmosis; Syndesmotic injury.

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Conflict of interest statement

Declarations. Commissioned illustrations: Maykon de Jesus Laveli Barros and Margareth de Castro Baldissera Moreira. Ethics approval, compliance with ethical standards and consent to participate: This work is in accordance with the Declaration of Helsinki and approval from the Institutional Review Board was obtained (IRB protocol 62100016.5.0 000.0071). Conflict of interest: The authors declare no competing interests.

References

    1. Kemler E, van de Port I, Valkenberg H, Hoes AW, Backx FJG. Ankle injuries in the Netherlands: trends over 10–25 years. Scand J Med Sci Sports. 2015;25:331–7. - PubMed - DOI
    1. Waterman BR, Owens BD, Davey S, Zacchilli MA, Belmont PJ. The epidemiology of ankle sprains in the United States. Journal of Bone and Joint Surgery - Series A. 2010;92:2279–84.
    1. Fong DT-P, Hong Y, Chan L-K, Yung PS-H, Chan K-M. A systematic review on ankle injury and ankle sprain in sports. Sports Med. 2007;37:73–94.
    1. Gerber JP, Williams GN, Scoville CR, Arciero RA, Taylor DC. Persistent disability associated with ankle sprains: a prospective examination of an athletic population. Foot Ankle Int. 1998;19:653–60. - PubMed - DOI
    1. Maltese L, Denaro V, Ciuffreda M, van Dijk CN, Longo UG, Florio P, et al. Classification and diagnosis of acute isolated syndesmotic injuries: ESSKA-AFAS consensus and guidelines. Knee Surg Sports Traumatol Arthrosc. 2015;24:1200–16. - PubMed

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