Vinblastine blocks stimulation-dependent vesicle redistribution in incubated synaptosomes
- PMID: 4066186
- DOI: 10.3109/00207458509070825
Vinblastine blocks stimulation-dependent vesicle redistribution in incubated synaptosomes
Abstract
Rat cortical synaptosomes were depolarized by the addition of protoveratrine to the incubating medium. The resulting synaptic vesicle aggregation near the synaptic cleft was prevented by vinblastine. Electron microscopy of both routine- and phosphotungstic acid-treated materials suggests the involvement of cytoskeletal structures in stimulation-dependent vesicle redistribution.
Similar articles
-
The effect of pentobarbital, chloralhydrate, ether and protoveratrine on the distribution of synaptic vesicles in rat cortical synaptosomes.Exp Brain Res. 1978 Sep 15;33(1):91-99. doi: 10.1007/BF00238797. Exp Brain Res. 1978. PMID: 700002
-
The morphology of microtubules in incubated synaptosomes. Effect of low temperature and vinblastine.Exp Brain Res. 1979 Apr 2;35(2):387-93. doi: 10.1007/BF00236622. Exp Brain Res. 1979. PMID: 436998
-
[Electron microscopic-cytochemical study of the effect of vinblastine on synaptosome adenylate cyclase in the rat cerebral cortex].Tsitologiia. 1989 Mar;31(3):282-6. Tsitologiia. 1989. PMID: 2749900 Russian.
-
Influences of colchicine and vinblastine on the uptake of 5-hydroxytryptamine and norepinephrine by rat brain synaptosomes and small vesicle fractions.J Neurochem. 1975 Jun;24(6):1257-9. doi: 10.1111/j.1471-4159.1975.tb03907.x. J Neurochem. 1975. PMID: 1127437 No abstract available.
-
Pharmacological and ultrastructural maturation of serotonergic synapses during ontogeny.Med Biol. 1975 Feb;53(1):1-14. Med Biol. 1975. PMID: 1095838 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources