An automated method for studying exploratory and stereotyped behaviour in rats
- PMID: 406630
- DOI: 10.1007/BF00426711
An automated method for studying exploratory and stereotyped behaviour in rats
Abstract
A technique is described for studying exploratory as well as stereotyped behaviour in rats using an automated hole-board. Both visual and automated recordings can be employed using the technique. Hole dipping is monitored automatically using an infra-red detector system. Repetitive patterns of hole-dipping are used as parameters of stereotyped behaviour while the more random patterns of hole-dipping are used as parameters of exploration. There was a high significant correlation between the records of hole-dipping behaviour as recorded visually and automatically. There was also a high significant correlation between the measures of repetitiveness/randomness of hole-dipping behaviour from automatic and visual recordings. The pattern and levels of hole-dipping conformed with expectations both as regards changes with time and with increasing doses of dl-amphetamine.
Similar articles
-
The effects of psychotropic drugs on exploratory and stereotyped behaviour of rats studied on a hole-board.Psychopharmacology (Berl). 1977 Nov 24;55(1):67-74. doi: 10.1007/BF00432819. Psychopharmacology (Berl). 1977. PMID: 414263
-
Validity of head-dipping as a measure of exploration in a modified hole-board.Psychopharmacologia. 1975 Oct 14;44(1):53-9. doi: 10.1007/BF00421184. Psychopharmacologia. 1975. PMID: 1197580
-
Exploration in immature rats: effects of drugs.Dev Psychobiol. 1978 Sep;11(5):405-12. doi: 10.1002/dev.420110504. Dev Psychobiol. 1978. PMID: 150988
-
Propionic acid induced behavioural effects of relevance to autism spectrum disorder evaluated in the hole board test with rats.Prog Neuropsychopharmacol Biol Psychiatry. 2020 Mar 8;97:109794. doi: 10.1016/j.pnpbp.2019.109794. Epub 2019 Oct 19. Prog Neuropsychopharmacol Biol Psychiatry. 2020. PMID: 31639413
-
Stereotyped behaviour in animals induced by stimulant drugs or by a restricted cage environment: relation to disintegrated behaviour, brain dopamine and psychiatric disease.Yakubutsu Seishin Kodo. 1988 Jun;8(2):313-27. Yakubutsu Seishin Kodo. 1988. PMID: 3064493 Review.
Cited by
-
Behavioural effects of electrolytic and 6-hydroxydopamine lesions of the accumbens and caudate-putamen nuclei.Psychopharmacology (Berl). 1982;76(4):33-40. doi: 10.1007/BF00449121. Psychopharmacology (Berl). 1982. PMID: 6812107
-
The effects of psychotropic drugs on exploratory and stereotyped behaviour of rats studied on a hole-board.Psychopharmacology (Berl). 1977 Nov 24;55(1):67-74. doi: 10.1007/BF00432819. Psychopharmacology (Berl). 1977. PMID: 414263
-
Another look at amphetamine-induced stereotyped locomotor activity in rats using a new statistic to measure locomotor stereotypy.Psychopharmacology (Berl). 1989;97(1):74-9. doi: 10.1007/BF00443416. Psychopharmacology (Berl). 1989. PMID: 2496430
-
Behavioural responses to stereotactically controlled injections of monoamine neurotransmitters into the accumbens and caudate-putamen nuclei.Psychopharmacology (Berl). 1980;71(3):227-35. doi: 10.1007/BF00433056. Psychopharmacology (Berl). 1980. PMID: 6109349
-
Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate.Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5052-6. doi: 10.1073/pnas.1117881109. Epub 2012 Mar 12. Proc Natl Acad Sci U S A. 2012. PMID: 22411800 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources